Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Research Project (R01)
Project #
7R01ES006887-02
Application #
2155822
Study Section
Toxicology Subcommittee 2 (TOX)
Project Start
1994-07-01
Project End
1997-06-30
Budget Start
1995-05-01
Budget End
1995-06-30
Support Year
2
Fiscal Year
1995
Total Cost
Indirect Cost
Name
University of Illinois at Chicago
Department
Pharmacology
Type
Schools of Pharmacy
DUNS #
121911077
City
Chicago
State
IL
Country
United States
Zip Code
60612
Mandlekar, S; Yu, R; Tan, T H et al. (2000) Activation of caspase-3 and c-Jun NH2-terminal kinase-1 signaling pathways in tamoxifen-induced apoptosis of human breast cancer cells. Cancer Res 60:5995-6000
Shtil, A A; Mandlekar, S; Yu, R et al. (1999) Differential regulation of mitogen-activated protein kinases by microtubule-binding agents in human breast cancer cells. Oncogene 18:377-84
Lei, W; Yu, R; Mandlekar, S et al. (1998) Induction of apoptosis and activation of interleukin 1beta-converting enzyme/Ced-3 protease (caspase-3) and c-Jun NH2-terminal kinase 1 by benzo(a)pyrene. Cancer Res 58:2102-6
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Yu, R; Tan, T H; Kong, A T (1997) Butylated hydroxyanisole and its metabolite tert-butylhydroquinone differentially regulate mitogen-activated protein kinases. The role of oxidative stress in the activation of mitogen-activated protein kinases by phenolic antioxidants. J Biol Chem 272:28962-70
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Fei, P; Matwyshyn, G A; Rushmore, T H et al. (1996) Transcription regulation of rat glutathione S-transferase Ya subunit gene expression by chemopreventive agents. Pharm Res 13:1043-8
Hellriegel, E T; Matwyshyn, G A; Fei, P et al. (1996) Regulation of gene expression of various phase I and phase II drug-metabolizing enzymes by tamoxifen in rat liver. Biochem Pharmacol 52:1561-8

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