Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Research Project (R01)
Project #
5R01EY003621-16
Application #
2158878
Study Section
Visual Sciences C Study Section (VISC)
Project Start
1981-09-01
Project End
1999-08-31
Budget Start
1996-09-01
Budget End
1997-08-31
Support Year
16
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of South Alabama
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
City
Mobile
State
AL
Country
United States
Zip Code
36688
Fillmore, Rebecca A; Nelson, Shannon E; Lausch, Robert N et al. (2003) Differential regulation of ENA-78 and GCP-2 gene expression in human corneal keratocytes and epithelial cells. Invest Ophthalmol Vis Sci 44:3432-7
Cubitt, C L; Lausch, R N; Oakes, J E (2001) Synthesis of type II interleukin-1 receptors by human corneal epithelial cells but not by keratocytes. Invest Ophthalmol Vis Sci 42:701-4
Bevans-Nelson, S E; Lausch, R N; Oakes, J E (2001) Tumor necrosis factor-alpha and not interleukin-1alpha is the dominant inducer of matrix metalloproteinase-9 synthesis in human corneal cells. Exp Eye Res 73:403-7
Tran, M T; Ritchie, M H; Lausch, R N et al. (2000) Calcitonin gene-related peptide induces IL-8 synthesis in human corneal epithelial cells. J Immunol 164:4307-12
Cubitt, C L; Lausch, R N; Oakes, J E (1997) Differential induction of GRO alpha gene expression in human corneal epithelial cells and keratocytes exposed to proinflammatory cytokines. Invest Ophthalmol Vis Sci 38:1149-58
Tran, M T; Tellaetxe-Isusi, M; Elner, V et al. (1996) Proinflammatory cytokines induce RANTES and MCP-1 synthesis in human corneal keratocytes but not in corneal epithelial cells. Beta-chemokine synthesis in corneal cells. Invest Ophthalmol Vis Sci 37:987-96
Su, Y H; Yan, X T; Oakes, J E et al. (1996) Protective antibody therapy is associated with reduced chemokine transcripts in herpes simplex virus type 1 corneal infection. J Virol 70:1277-81
Cubitt, C L; Lausch, R N; Oakes, J E (1995) Differences in interleukin-6 gene expression between cultured human corneal epithelial cells and keratocytes. Invest Ophthalmol Vis Sci 36:330-6
Oakes, J E; Monteiro, C A; Cubitt, C L et al. (1993) Induction of interleukin-8 gene expression is associated with herpes simplex virus infection of human corneal keratocytes but not human corneal epithelial cells. J Virol 67:4777-84
Cubitt, C L; Tang, Q; Monteiro, C A et al. (1993) IL-8 gene expression in cultures of human corneal epithelial cells and keratocytes. Invest Ophthalmol Vis Sci 34:3199-206

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