The ultimate objective of this research is to derive a faithful and economical representation of visual processes. The basic approach is to separate the visual processes into smaller and simpler functional units for study. The method depends on a behavioral means of exploiting a nonlinear process in the retina that partitions the visual system into separate compartments in a way that allows separate investigation of each compartment, and provides a reference point in the sequence of processes. The present proposal is to continue to exploit this and related methods. Specifically, the aims are to: measure spatially antagonistic processes at a site in the visual system close to the receptors; measure sensitivity to aperiodic spatial stimuli superimposed on background fields containing periodic stimuli like sinusoidally modulated gratings, to determine whether models derived for one stimulus domain work with stimuli outside that domain; establish whether the signal and noise that determine sensitivity can be separately measured by matching contrasts and by the slopes of the functions by which the matches are measured; determine the conditions necessary to restore the correct appearance of contrast after changes in the optical quality of the eye; and measure the components of involuntary eye movements that affect the motion of the receptors and, hence, vision.

Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Research Project (R01)
Project #
5R01EY004885-16
Application #
2888146
Study Section
Visual Sciences B Study Section (VISB)
Project Start
1984-04-01
Project End
2002-03-31
Budget Start
1999-04-01
Budget End
2000-03-31
Support Year
16
Fiscal Year
1999
Total Cost
Indirect Cost
Name
University of Rochester
Department
Miscellaneous
Type
Schools of Arts and Sciences
DUNS #
208469486
City
Rochester
State
NY
Country
United States
Zip Code
14627
Lee, Byeong-Taek; McPeek, Robert M (2013) The effects of distractors and spatial precues on covert visual search in macaque. Vision Res 76:43-9
Lee, Byeong-Taek; McPeek, Robert M (2013) Reprint of: The effects of distractors and spatial precues on covert visual search in macaque. Vision Research, 76, pp. 43-9. Vision Res 85:73-9
Khan, Aarlenne Z; Song, Joo-Hyun; McPeek, Robert M (2011) The eye dominates in guiding attention during simultaneous eye and hand movements. J Vis 11:9
Rainville, Stephane J M; Makous, Walter L; Scott-Samuel, Nicholas E (2005) Opponent-motion mechanisms are self-normalizing. Vision Res 45:1115-27
Fiser, Jozsef; Bex, Peter J; Makous, Walter (2003) Contrast conservation in human vision. Vision Res 43:2637-48
Rainville, Stephane J M; Kingdom, Frederick A A (2002) Scale invariance is driven by stimulus density. Vision Res 42:351-67
DeVries, Steven H; Qi, Xiaofeng; Smith, Robert et al. (2002) Electrical coupling between mammalian cones. Curr Biol 12:1900-7
Bex, Peter J; Makous, Walter (2002) Spatial frequency, phase, and the contrast of natural images. J Opt Soc Am A Opt Image Sci Vis 19:1096-106
Rainville, Stephane J M; Scott-Samuel, Nicholas E; Makous, Walter L (2002) The spatial properties of opponent-motion normalization. Vision Res 42:1727-38
O'Brien, H L; Tetewsky, S J; Avery, L M et al. (2001) Visual mechanisms of spatial disorientation in Alzheimer's disease. Cereb Cortex 11:1083-92

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