Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Research Project (R01)
Project #
1R01EY011135-01A1
Application #
2165421
Study Section
Visual Sciences A Study Section (VISA)
Project Start
1996-07-01
Project End
2000-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Southern California
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
041544081
City
Los Angeles
State
CA
Country
United States
Zip Code
90089
Gukasyan, Hovhannes J; Kim, Kwang-Jin; Lee, Vincent H L et al. (2007) Glutathione and its transporters in ocular surface defense. Ocul Surf 5:269-79
Gukasyan, Hovhannes J; Lee, Vincent H L; Simityan, Hagop et al. (2006) Thermodynamic stoichiometry of Na+-coupled glutathione transport. Can J Physiol Pharmacol 84:1223-7
Kannan, Ram; Gukasyan, Hovhannes J; Zhang, Wenzheng et al. (2004) Impairment of conjunctival glutathione secretion and ion transport by oxidative stress in an adenovirus type 5 ocular infection model of pigmented rabbits. Free Radic Biol Med 37:229-38
Gukasyan, Hovhannes J; Kannan, Ram; Lee, Vincent H L et al. (2003) Regulation of L-cystine transport and intracellular GSH level by a nitric oxide donor in primary cultured rabbit conjunctival epithelial cell layers. Invest Ophthalmol Vis Sci 44:1202-10
Gukasyan, Hovhannes J; Kim, Kwang-Jin; Kannan, Ram et al. (2003) Specialized protective role of mucosal glutathione in pigmented rabbit conjunctiva. Invest Ophthalmol Vis Sci 44:4427-38
Gukasyan, Hovhannes J; Lee, Vincent H L; Kim, Kwang-Jin et al. (2002) Net glutathione secretion across primary cultured rabbit conjunctival epithelial cell layers. Invest Ophthalmol Vis Sci 43:1154-61
Kannan, R; Tang, D; Hu, J et al. (2001) Glutathione transport in human retinal pigment epithelial (HRPE) cells: apical localization of sodium-dependent gsh transport. Exp Eye Res 72:661-6
Kannan, R; Ouyang, B; Wawrousek, E et al. (2001) Regulation of GSH in alphaA-expressing human lens epithelial cell lines and in alphaA knockout mouse lenses. Invest Ophthalmol Vis Sci 42:409-16
Kannan, R; Stolz, A; Ji, Q et al. (2001) Vitamin C transport in human lens epithelial cells: evidence for the presence of SVCT2. Exp Eye Res 73:159-65
Lu, S C; Bao, Y; Huang, Z Z et al. (1999) Regulation of gamma-glutamylcysteine synthetase subunit gene expression in retinal Muller cells by oxidative stress. Invest Ophthalmol Vis Sci 40:1776-82

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