Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM031528-12
Application #
2176161
Study Section
Molecular Biology Study Section (MBY)
Project Start
1982-08-01
Project End
1996-12-31
Budget Start
1995-07-01
Budget End
1996-12-31
Support Year
12
Fiscal Year
1995
Total Cost
Indirect Cost
Name
Case Western Reserve University
Department
Biochemistry
Type
Schools of Medicine
DUNS #
077758407
City
Cleveland
State
OH
Country
United States
Zip Code
44106
Yu, Yang; Maroney, Patricia A; Denker, John A et al. (2008) Dynamic regulation of alternative splicing by silencers that modulate 5'splice site competition. Cell 135:1224-36
Romfo, C M; Maroney, P A; Wu, S et al. (2001) 3' splice site recognition in nematode trans-splicing involves enhancer-dependent recruitment of U2 snRNP. RNA 7:785-92
Maroney, P A; Romfo, C M; Nilsen, T W (2000) Functional recognition of 5' splice site by U4/U6.U5 tri-snRNP defines a novel ATP-dependent step in early spliceosome assembly. Mol Cell 6:317-28
Maroney, P A; Romfo, C M; Nilsen, T W (2000) Nuclease protection of RNAs containing site-specific labels: a rapid method for mapping RNA-protein interactions. RNA 6:1905-9
Denker, J A; Maroney, P A; Yu, Y T et al. (1996) Multiple requirements for nematode spliced leader RNP function in trans-splicing. RNA 2:746-55
Maroney, P A; Yu, Y T; Jankowska, M et al. (1996) Direct analysis of nematode cis- and trans-spliceosomes: a functional role for U5 snRNA in spliced leader addition trans-splicing and the identification of novel Sm snRNPs. RNA 2:735-45
Yu, Y T; Maroney, P A; Darzynkiwicz, E et al. (1995) U6 snRNA function in nuclear pre-mRNA splicing: a phosphorothioate interference analysis of the U6 phosphate backbone. RNA 1:46-54
Maroney, P A; Denker, J A; Darzynkiewicz, E et al. (1995) Most mRNAs in the nematode Ascaris lumbricoides are trans-spliced: a role for spliced leader addition in translational efficiency. RNA 1:714-23
Nilsen, T W (1993) Trans-splicing of nematode premessenger RNA. Annu Rev Microbiol 47:413-40
Yu, Y T; Maroney, P A; Nilsen, T W (1993) Functional reconstitution of U6 snRNA in nematode cis- and trans-splicing: U6 can serve as both a branch acceptor and a 5' exon. Cell 75:1049-59

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