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Lardinois, Olivier M; Maltby, David A; Medzihradszky, Katalin F et al. (2009) Spin scavenging analysis of myoglobin protein-centered radicals using stable nitroxide radicals: characterization of oxoammonium cation-induced modifications. Chem Res Toxicol 22:1034-49
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Meitzler, Jennifer L; Ortiz de Montellano, Paul R (2009) Caenorhabditis elegans and human dual oxidase 1 (DUOX1) ""peroxidase"" domains: insights into heme binding and catalytic activity. J Biol Chem 284:18634-43
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Ortiz de Montellano, Paul R (2008) Mechanism and role of covalent heme binding in the CYP4 family of P450 enzymes and the mammalian peroxidases. Drug Metab Rev 40:405-26
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Wojciechowski, Grzegorz; de Montellano, Paul R Ortiz (2007) Radical energies and the regiochemistry of addition to heme groups. Methylperoxy and nitrite radical additions to the heme of horseradish peroxidase. J Am Chem Soc 129:1663-72
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Huang, Liusheng; Ortiz de Montellano, Paul R (2007) Arthromyces ramosus peroxidase produces two chlorinating species. Biochem Biophys Res Commun 355:581-6
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Huang, Liusheng; Wojciechowski, Grzegorz; Ortiz de Montellano, Paul R (2006) Role of heme-protein covalent bonds in mammalian peroxidases. Protection of the heme by a single engineered heme-protein link in horseradish peroxidase. J Biol Chem 281:18983-8
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Huang, Liusheng; Ortiz de Montellano, Paul R (2006) Heme-protein covalent bonds in peroxidases and resistance to heme modification during halide oxidation. Arch Biochem Biophys 446:77-83
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Ghiladi, Reza A; Medzihradszky, Katalin F; Rusnak, Frank M et al. (2005) Correlation between isoniazid resistance and superoxide reactivity in mycobacterium tuberculosis KatG. J Am Chem Soc 127:13428-42
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Wojciechowski, Grzegorz; Huang, Liusheng; Ortiz de Montellano, Paul R (2005) Autocatalytic modification of the prosthetic heme of horseradish but not lactoperoxidase by thiocyanate oxidation products. A role for heme-protein covalent cross-linking. J Am Chem Soc 127:15871-9
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Ghiladi, Reza A; Knudsen, Giselle M; Medzihradszky, Katalin F et al. (2005) The Met-Tyr-Trp cross-link in Mycobacterium tuberculosis catalase-peroxidase (KatG): autocatalytic formation and effect on enzyme catalysis and spectroscopic properties. J Biol Chem 280:22651-63
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