Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM032703-12
Application #
2176704
Study Section
Molecular Cytology Study Section (CTY)
Project Start
1983-12-01
Project End
1997-11-30
Budget Start
1994-12-01
Budget End
1997-11-30
Support Year
12
Fiscal Year
1995
Total Cost
Indirect Cost
Name
University of California San Diego
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
077758407
City
La Jolla
State
CA
Country
United States
Zip Code
92093
Darsow, T; Burd, C G; Emr, S D (1998) Acidic di-leucine motif essential for AP-3-dependent sorting and restriction of the functional specificity of the Vam3p vacuolar t-SNARE. J Cell Biol 142:913-22
Gaynor, E C; Chen, C Y; Emr, S D et al. (1998) ARF is required for maintenance of yeast Golgi and endosome structure and function. Mol Biol Cell 9:653-70
Gaynor, E C; Graham, T R; Emr, S D (1998) COPI in ER/Golgi and intra-Golgi transport: do yeast COPI mutants point the way? Biochim Biophys Acta 1404:33-51
Cowles, C R; Odorizzi, G; Payne, G S et al. (1997) The AP-3 adaptor complex is essential for cargo-selective transport to the yeast vacuole. Cell 91:109-18
Darsow, T; Rieder, S E; Emr, S D (1997) A multispecificity syntaxin homologue, Vam3p, essential for autophagic and biosynthetic protein transport to the vacuole. J Cell Biol 138:517-29
Cowles, C R; Snyder, W B; Burd, C G et al. (1997) Novel Golgi to vacuole delivery pathway in yeast: identification of a sorting determinant and required transport component. EMBO J 16:2769-82
Radisky, D C; Snyder, W B; Emr, S D et al. (1997) Characterization of VPS41, a gene required for vacuolar trafficking and high-affinity iron transport in yeast. Proc Natl Acad Sci U S A 94:5662-6
Rieder, S E; Emr, S D (1997) A novel RING finger protein complex essential for a late step in protein transport to the yeast vacuole. Mol Biol Cell 8:2307-27
Gaynor, E C; Emr, S D (1997) COPI-independent anterograde transport: cargo-selective ER to Golgi protein transport in yeast COPI mutants. J Cell Biol 136:789-802
Babst, M; Sato, T K; Banta, L M et al. (1997) Endosomal transport function in yeast requires a novel AAA-type ATPase, Vps4p. EMBO J 16:1820-31

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