Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
2R01GM032967-13
Application #
2176803
Study Section
Microbial Physiology and Genetics Subcommittee 2 (MBC)
Project Start
1983-12-01
Project End
1999-11-30
Budget Start
1995-12-05
Budget End
1996-11-30
Support Year
13
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Harvard University
Department
Genetics
Type
Schools of Medicine
DUNS #
082359691
City
Boston
State
MA
Country
United States
Zip Code
02115
Doris, Stephen M; Chuang, James; Viktorovskaya, Olga et al. (2018) Spt6 Is Required for the Fidelity of Promoter Selection. Mol Cell 72:687-699.e6
Shetty, Ameet; Kallgren, Scott P; Demel, Carina et al. (2017) Spt5 Plays Vital Roles in the Control of Sense and Antisense Transcription Elongation. Mol Cell 66:77-88.e5
Winston, Fred; Koshland, Douglas (2016) Back to the Future: Mutant Hunts Are Still the Way To Go. Genetics 203:1007-10
DeGennaro, Christine M; Alver, Burak H; Marguerat, Samuel et al. (2013) Spt6 regulates intragenic and antisense transcription, nucleosome positioning, and histone modifications genome-wide in fission yeast. Mol Cell Biol 33:4779-92
Chang, Jennifer S; Winston, Fred (2013) Cell-cycle perturbations suppress the slow-growth defect of spt10? mutants in Saccharomyces cerevisiae. G3 (Bethesda) 3:573-83
Rando, Oliver J; Winston, Fred (2012) Chromatin and transcription in yeast. Genetics 190:351-87
Ivanovska, Iva; Jacques, Pierre-Étienne; Rando, Oliver J et al. (2011) Control of chromatin structure by spt6: different consequences in coding and regulatory regions. Mol Cell Biol 31:531-41
Chang, Jennifer S; Winston, Fred (2011) Spt10 and Spt21 are required for transcriptional silencing in Saccharomyces cerevisiae. Eukaryot Cell 10:118-29
Kiely, Christine M; Marguerat, Samuel; Garcia, Jennifer F et al. (2011) Spt6 is required for heterochromatic silencing in the fission yeast Schizosaccharomyces pombe. Mol Cell Biol 31:4193-204
Libuda, Diana E; Winston, Fred (2010) Alterations in DNA replication and histone levels promote histone gene amplification in Saccharomyces cerevisiae. Genetics 184:985-97

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