Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM038242-02
Application #
3294461
Study Section
Molecular Biology Study Section (MBY)
Project Start
1987-04-01
Project End
1992-03-31
Budget Start
1988-04-01
Budget End
1989-03-31
Support Year
2
Fiscal Year
1988
Total Cost
Indirect Cost
Name
Cold Spring Harbor Laboratory
Department
Type
DUNS #
065968786
City
Cold Spring Harbor
State
NY
Country
United States
Zip Code
11724
Rotondo, G; Frendewey, D (2001) Pac1 ribonuclease of Schizosaccharomyces pombe. Methods Enzymol 342:168-93
McDonald, W H; Ohi, R; Smelkova, N et al. (1999) Myb-related fission yeast cdc5p is a component of a 40S snRNP-containing complex and is essential for pre-mRNA splicing. Mol Cell Biol 19:5352-62
Potashkin, J; Kim, D; Fons, M et al. (1998) Cell-division-cycle defects associated with fission yeast pre-mRNA splicing mutants. Curr Genet 34:153-63
Rotondo, G; Gillespie, M; Frendewey, D (1995) Rescue of the fission yeast snRNA synthesis mutant snm1 by overexpression of the double-strand-specific Pac1 ribonuclease. Mol Gen Genet 247:698-708
Potashkin, J; Frendewey, D (1990) A mutation in a single gene of Schizosaccharomyces pombe affects the expression of several snRNAs and causes defects in RNA processing. EMBO J 9:525-34
Frendewey, D; Barta, I; Gillespie, M et al. (1990) Schizosaccharomyces U6 genes have a sequence within their introns that matches the B box consensus of tRNA internal promoters. Nucleic Acids Res 18:2025-32
Potashkin, J; Frendewey, D (1989) Splicing of the U6 RNA precursor is impaired in fission yeast pre-mRNA splicing mutants. Nucleic Acids Res 17:7821-31
Potashkin, J; Li, R; Frendewey, D (1989) Pre-mRNA splicing mutants of Schizosaccharomyces pombe. EMBO J 8:551-9
Erster, S H; Finn, L A; Frendewey, D A et al. (1988) Use of RNase H and primer extension to analyze RNA splicing. Nucleic Acids Res 16:5999-6014