Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM045134-12
Application #
6636019
Study Section
Physiological Chemistry Study Section (PC)
Program Officer
Anderson, James J
Project Start
1991-08-01
Project End
2004-03-31
Budget Start
2003-03-01
Budget End
2004-03-31
Support Year
12
Fiscal Year
2003
Total Cost
$243,834
Indirect Cost
Name
University of Washington
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
605799469
City
Seattle
State
WA
Country
United States
Zip Code
98195
Mikula, Michal; Bomsztyk, Karol (2011) Direct recruitment of ERK cascade components to inducible genes is regulated by heterogeneous nuclear ribonucleoprotein (hnRNP) K. J Biol Chem 286:9763-75
Nelson, Joel; Denisenko, Oleg; Bomsztyk, Karol (2011) Profiling RNA polymerase II using the fast chromatin immunoprecipitation method. Methods Mol Biol 703:219-34
Aker, Mari; Bomsztyk, Karol; Emery, David W (2010) Poly(ADP-ribose) polymerase-1 (PARP-1) contributes to the barrier function of a vertebrate chromatin insulator. J Biol Chem 285:37589-97
Nelson, Joel; Denisenko, Oleg; Bomsztyk, Karol (2009) The fast chromatin immunoprecipitation method. Methods Mol Biol 567:45-57
Naito, Masayo; Bomsztyk, Karol; Zager, Richard A (2009) Renal ischemia-induced cholesterol loading: transcription factor recruitment and chromatin remodeling along the HMG CoA reductase gene. Am J Pathol 174:54-62
Naito, Masayo; Zager, Richard A; Bomsztyk, Karol (2009) BRG1 increases transcription of proinflammatory genes in renal ischemia. J Am Soc Nephrol 20:1787-96
Zager, Richard A; Johnson, Ali C M; Naito, Masayo et al. (2008) Growth and development alter susceptibility to acute renal injury. Kidney Int 74:674-8
Naito, Masayo; Bomsztyk, Karol; Zager, Richard A (2008) Endotoxin mediates recruitment of RNA polymerase II to target genes in acute renal failure. J Am Soc Nephrol 19:1321-30
Flanagin, Steve; Nelson, Joel D; Castner, David G et al. (2008) Microplate-based chromatin immunoprecipitation method, Matrix ChIP: a platform to study signaling of complex genomic events. Nucleic Acids Res 36:e17
Zager, Richard A; Johnson, Ali C M; Naito, Masayo et al. (2008) Maleate nephrotoxicity: mechanisms of injury and correlates with ischemic/hypoxic tubular cell death. Am J Physiol Renal Physiol 294:F187-97

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