Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM050007-02
Application #
2187576
Study Section
Tropical Medicine and Parasitology Study Section (TMP)
Project Start
1994-12-01
Project End
1997-11-30
Budget Start
1995-12-01
Budget End
1996-11-30
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
University of Illinois Urbana-Champaign
Department
Other Basic Sciences
Type
Schools of Arts and Sciences
DUNS #
041544081
City
Champaign
State
IL
Country
United States
Zip Code
61820

  Publications

Wen, Zhimou; Baudry, Jerome; Berenbaum, May R et al. (2005) Ile115Leu mutation in the SRS1 region of an insect cytochrome P450 (CYP6B1) compromises substrate turnover via changes in a predicted product release channel. Protein Eng Des Sel 18:191-9
Brown, Rebecca Petersen; McDonnell, Cynthia M; Berenbaum, May R et al. (2005) Regulation of an insect cytochrome P450 monooxygenase gene (CYP6B1) by aryl hydrocarbon and xanthotoxin response cascades. Gene 358:39-52
Petersen Brown, R; Berenbaum, M R; Schuler, M A (2004) Transcription of a lepidopteran cytochrome P450 promoter is modulated by multiple elements in its 5' UTR and repressed by 20-hydroxyecdysone. Insect Mol Biol 13:337-47
Li, W; Zangerl, A R; Schuler, M A et al. (2004) Characterization and evolution of furanocoumarin-inducible cytochrome P450s in the parsnip webworm, Depressaria pastinacella. Insect Mol Biol 13:603-13
Li, Xianchun; Baudry, Jerome; Berenbaum, May R et al. (2004) Structural and functional divergence of insect CYP6B proteins: From specialist to generalist cytochrome P450. Proc Natl Acad Sci U S A 101:2939-44
Pan, Liping; Wen, Zhimou; Baudry, Jerome et al. (2004) Identification of variable amino acids in the SRS1 region of CYP6B1 modulating furanocoumarin metabolism. Arch Biochem Biophys 422:31-41
Baudry, Jerome; Li, Weimin; Pan, Liping et al. (2003) Molecular docking of substrates and inhibitors in the catalytic site of CYP6B1, an insect cytochrome p450 monooxygenase. Protein Eng 16:577-87
Civjan, Natanya R; Bayburt, Timothy H; Schuler, Mary A et al. (2003) Direct solubilization of heterologously expressed membrane proteins by incorporation into nanoscale lipid bilayers. Biotechniques 35:556-60, 562-3
Li, Weimin; Schuler, Mary A; Berenbaum, May R (2003) Diversification of furanocoumarin-metabolizing cytochrome P450 monooxygenases in two papilionids: Specificity and substrate encounter rate. Proc Natl Acad Sci U S A 100 Suppl 2:14593-8
Wen, Zhimou; Pan, Liping; Berenbaum, May R et al. (2003) Metabolism of linear and angular furanocoumarins by Papilio polyxenes CYP6B1 co-expressed with NADPH cytochrome P450 reductase. Insect Biochem Mol Biol 33:937-47

Showing the most recent 10 out of 14 publications