Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
1R01GM050791-01A2
Application #
2188873
Study Section
Biochemistry Study Section (BIO)
Project Start
1996-05-01
Project End
2000-04-30
Budget Start
1996-05-01
Budget End
1997-04-30
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Michigan Ann Arbor
Department
Psychiatry
Type
Schools of Medicine
DUNS #
791277940
City
Ann Arbor
State
MI
Country
United States
Zip Code
48109
Taylor, Merritt K; Ahmed, Rehan; Begley, Michael et al. (2002) Autoinhibition and isoform-specific dominant negative inhibition of the type II cGMP-dependent protein kinase. J Biol Chem 277:37242-53
Stansberry, J; Baude, E J; Taylor, M K et al. (2001) A cGMP-dependent protein kinase is implicated in wild-type motility in C. elegans. J Neurochem 76:1177-87
Taylor, M K; Uhler, M D (2000) The amino-terminal cyclic nucleotide binding site of the type II cGMP-dependent protein kinase is essential for full cyclic nucleotide-dependent activation. J Biol Chem 275:28053-62
Gamm, D M; Barthel, L K; Raymond, P A et al. (2000) Localization of cGMP-dependent protein kinase isoforms in mouse eye. Invest Ophthalmol Vis Sci 41:2766-73
Hall, K U; Collins, S P; Gamm, D M et al. (1999) Phosphorylation-dependent inhibition of protein phosphatase-1 by G-substrate. A Purkinje cell substrate of the cyclic GMP-dependent protein kinase. J Biol Chem 274:3485-95