Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM053235-02
Application #
2192560
Study Section
Special Emphasis Panel (ZRG7-SB (01))
Project Start
1995-08-01
Project End
1999-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Loyola University Chicago
Department
Physiology
Type
Schools of Medicine
DUNS #
791277940
City
Maywood
State
IL
Country
United States
Zip Code
60153
Sayeed, Mohammed M (2005) Inflammatory/cardiovascular-metabolic responses in a rat model of burn injury with superimposed infection. Shock 24 Suppl 1:40-4
Al-Ghoul, Walid M; Khan, Mehdi; Fazal, Nadeem et al. (2004) Mechanisms of postburn intestinal barrier dysfunction in the rat: roles of epithelial cell renewal, E-cadherin, and neutrophil extravasation. Crit Care Med 32:1730-9
Choudhry, Mashkoor A; Mao, Haihong; Haque, Farah et al. (2002) Role of NFAT and AP-1 in PGE2-mediated T cell suppression in burn injury. Shock 18:212-6
Fazal, N; Al-Ghoul, W M; Choudhry, M A et al. (2001) PAF receptor antagonist modulates neutrophil responses with thermal injury in vivo. Am J Physiol Cell Physiol 281:C1310-7
Choudhry, M A; Sir, O; Sayeed, M M (2001) TGF-beta abrogates TCR-mediated signaling by upregulating tyrosine phosphatases in T cells. Shock 15:193-9
Sayeed, M M (2000) Signaling mechanisms of altered cellular responses in trauma, burn, and sepsis: role of Ca2+. Arch Surg 135:1432-42
Fazal, N; Shamim, M; Khan, S S et al. (2000) Neutrophil depletion in rats reduces burn-injury induced intestinal bacterial translocation. Crit Care Med 28:1550-5
Fazal, N; Shamim, M; Zagorski, J et al. (2000) CINC blockade prevents neutrophil Ca(2+) signaling upregulation and gut bacterial translocation in thermal injury. Biochim Biophys Acta 1535:50-9
Fazal, N; Knaus, U G; Sabeh, F et al. (1999) Enhanced expression of neutrophil NADPH oxidase components in intestine of rats after burn injury. Shock 12:438-42
Choudhry, M A; Ahmed, Z; Sayeed, M M (1999) PGE(2)-mediated inhibition of T cell p59(fyn) is independent of cAMP. Am J Physiol 277:C302-9

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