Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
1R01GM054048-01
Application #
2193443
Study Section
Bio-Organic and Natural Products Chemistry Study Section (BNP)
Project Start
1996-04-01
Project End
2000-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Florida
Department
Chemistry
Type
Schools of Arts and Sciences
DUNS #
073130411
City
Gainesville
State
FL
Country
United States
Zip Code
32611
Benner, Steven A (2012) Aesthetics in synthesis and synthetic biology. Curr Opin Chem Biol 16:581-5
Yang, Zunyi; Hutter, Daniel; Sheng, Pinpin et al. (2006) Artificially expanded genetic information system: a new base pair with an alternative hydrogen bonding pattern. Nucleic Acids Res 34:6095-101
Martinot, Theodore A; Benner, Steven A (2004) Artificial genetic systems: exploiting the ""aromaticity"" formalism to improve the tautomeric ratio for isoguanosine derivatives. J Org Chem 69:3972-5
Sismour, A Michael; Lutz, Stefan; Park, Jeong-Ho et al. (2004) PCR amplification of DNA containing non-standard base pairs by variants of reverse transcriptase from Human Immunodeficiency Virus-1. Nucleic Acids Res 32:728-35
Held, Heike A; Roychowdhury, Abhijit; Benner, Steven A (2003) C-5 modified nucleosides: direct insertion of alkynyl-thio functionality in pyrimidines. Nucleosides Nucleotides Nucleic Acids 22:391-404
Hutter, Daniel; Benner, Steven A (2003) Expanding the genetic alphabet: non-epimerizing nucleoside with the pyDDA hydrogen-bonding pattern. J Org Chem 68:9839-42
Geyer, C Ronald; Battersby, Thomas R; Benner, Steven A (2003) Nucleobase pairing in expanded Watson-Crick-like genetic information systems. Structure 11:1485-98
Held, Heike A; Benner, Steven A (2002) Challenging artificial genetic systems: thymidine analogs with 5-position sulfur functionality. Nucleic Acids Res 30:3857-69
Benner, Steven A; Hutter, Daniel (2002) Phosphates, DNA, and the search for nonterrean life: a second generation model for genetic molecules. Bioorg Chem 30:62-80
Huang, Zhen; Benner, Steven A (2002) Oligodeoxyribonucleotide analogues with bridging dimethylene sulfide, sulfoxide, and sulfone groups. Toward a second-generation model of nucleic acid structure. J Org Chem 67:3996-4013

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