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Dunican, Brian F; Hiller, David A; Strobel, Scott A (2015) Transition State Charge Stabilization and Acid-Base Catalysis of mRNA Cleavage by the Endoribonuclease RelE. Biochemistry 54:7048-57
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Smith, Kathryn D; Gordon, Patricia B; Rivetta, Alberto et al. (2015) Yeast Fex1p Is a Constitutively Expressed Fluoride Channel with Functional Asymmetry of Its Two Homologous Domains. J Biol Chem 290:19874-87
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Griffin, Meghan A; Davis, Jared H; Strobel, Scott A (2013) Bacterial toxin RelE: a highly efficient ribonuclease with exquisite substrate specificity using atypical catalytic residues. Biochemistry 52:8633-42
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Carrasco, Nicolas; Hiller, David A; Strobel, Scott A (2011) Minimal transition state charge stabilization of the oxyanion during peptide bond formation by the ribosome. Biochemistry 50:10491-8
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Davis, Jared H; Dunican, Brian F; Strobel, Scott A (2011) glmS Riboswitch binding to the glucosamine-6-phosphate ?-anomer shifts the pKa toward neutrality. Biochemistry 50:7236-42
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Hiller, David A; Singh, Vipender; Zhong, Minghong et al. (2011) A two-step chemical mechanism for ribosome-catalysed peptide bond formation. Nature 476:236-9
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Hiller, David A; Zhong, Minghong; Singh, Vipender et al. (2010) Transition states of uncatalyzed hydrolysis and aminolysis reactions of a ribosomal P-site substrate determined by kinetic isotope effects. Biochemistry 49:3868-78
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Kingery, David A; Pfund, Emmanuel; Voorhees, Rebecca M et al. (2008) An uncharged amine in the transition state of the ribosomal peptidyl transfer reaction. Chem Biol 15:493-500
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Zhong, Minghong; Strobel, Scott A (2008) Synthesis of isotopically labeled P-site substrates for the ribosomal peptidyl transferase reaction. J Org Chem 73:603-11
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Huang, Kevin S; Carrasco, Nicolas; Pfund, Emmanuel et al. (2008) Transition state chirality and role of the vicinal hydroxyl in the ribosomal peptidyl transferase reaction. Biochemistry 47:8822-7
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Showing the most recent 10 out of 29 publications
