Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Research Project (R01)
Project #
3R01HD029435-02S1
Application #
3330908
Study Section
Neurology B Subcommittee 2 (NEUB)
Project Start
1992-08-01
Project End
1995-07-31
Budget Start
1994-06-01
Budget End
1994-07-31
Support Year
2
Fiscal Year
1994
Total Cost
Indirect Cost
Name
Wake Forest University Health Sciences
Department
Type
Schools of Medicine
DUNS #
041418799
City
Winston-Salem
State
NC
Country
United States
Zip Code
27106
Houenou, L J; Blondet, B; Li, L et al. (1996) The paralyse mouse mutant: a new animal model of anterior horn motor neuron degeneration. J Neuropathol Exp Neurol 55:698-703
Houenou, L J; Li, L; Lei, M et al. (1996) Exogenous heat shock cognate protein Hsc 70 prevents axotomy-induced death of spinal sensory neurons. Cell Stress Chaperones 1:161-6
Li, L; Schatteman, G C; Oppenheim, R W et al. (1996) Altered development of spinal cord in the mouse mutant (Patch) lacking the PDGF receptor alpha-subunit gene. Brain Res Dev Brain Res 96:204-9
Houenou, L J; Oppenheim, R W; Li, L et al. (1996) Regulation of spinal motoneuron survival by GDNF during development and following injury. Cell Tissue Res 286:219-23
Li, L; Wu, W; Lin, L F et al. (1995) Rescue of adult mouse motoneurons from injury-induced cell death by glial cell line-derived neurotrophic factor. Proc Natl Acad Sci U S A 92:9771-5
Houenou, L J; Turner, P L; Li, L et al. (1995) A serine protease inhibitor, protease nexin I, rescues motoneurons from naturally occurring and axotomy-induced cell death. Proc Natl Acad Sci U S A 92:895-9
Lo, A C; Houenou, L J; Oppenheim, R W (1995) Apoptosis in the nervous system: morphological features, methods, pathology, and prevention. Arch Histol Cytol 58:139-49
Lo, A C; Li, L; Oppenheim, R W et al. (1995) Ciliary neurotrophic factor promotes the survival of spinal sensory neurons following axotomy but not during the period of programmed cell death. Exp Neurol 134:49-55
Houenou, L J; Li, L; Lo, A C et al. (1994) Naturally occurring and axotomy-induced motoneuron death and its prevention by neurotrophic agents: a comparison between chick and mouse. Prog Brain Res 102:217-26
Li, L; Oppenheim, R W; Lei, M et al. (1994) Neurotrophic agents prevent motoneuron death following sciatic nerve section in the neonatal mouse. J Neurobiol 25:759-66

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