Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Research Project (R01)
Project #
5R01HD031467-07
Application #
2204005
Study Section
Biochemical Endocrinology Study Section (BCE)
Project Start
1989-08-01
Project End
1998-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
7
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of California Los Angeles
Department
Obstetrics & Gynecology
Type
Schools of Medicine
DUNS #
119132785
City
Los Angeles
State
CA
Country
United States
Zip Code
90095
Singh, R; Pervin, S; Karimi, A et al. (2000) Arginase activity in human breast cancer cell lines: N(omega)-hydroxy-L-arginine selectively inhibits cell proliferation and induces apoptosis in MDA-MB-468 cells. Cancer Res 60:3305-12
Nathan, L; Pervin, S; Singh, R et al. (1999) Estradiol inhibits leukocyte adhesion and transendothelial migration in rabbits in vivo : possible mechanisms for gender differences in atherosclerosis. Circ Res 85:377-85
Hyun, J; Chaudhuri, G; Fukuto, J M (1999) The reductive metabolism of nitric oxide in hepatocytes: possible interaction with thiols. Drug Metab Dispos 27:1005-9
Amarnani, S; Sangrat, B; Chaudhuri, G (1999) Effects of selected endothelium-dependent vasodilators on fetoplacental vasculature: physiological implications. Am J Physiol 277:H842-7
Pervin, S; Singh, R; Rosenfeld, M E et al. (1998) Estradiol suppresses MCP-1 expression In vivo : implications for atherosclerosis. Arterioscler Thromb Vasc Biol 18:1575-82
Nathan, L; Chaudhuri, G (1997) Estrogens and atherosclerosis. Annu Rev Pharmacol Toxicol 37:477-515
Radziszewski, W; Chopra, M; Zembowicz, A et al. (1995) Nitric oxide donors induce extrusion of cyclic GMP from isolated human blood platelets by a mechanism which may be modulated by prostaglandins. Int J Cardiol 51:211-20
Chaudhuri, G; Cuevas, J; Buga, G M et al. (1993) NO is more important than PGI2 in maintaining low vascular tone in feto-placental vessels. Am J Physiol 265:H2036-43