This project will provide web-based tools for visualizing, navigating, and analyzing genomes and relationships between genomes. It will be directly useful to clinicians, molecular biologists, bioengineers, and others analyzing genome data in order to understand variant genotypes, comparative genomics, tumorigenesis, and other areas of biology that can be related to genes and genomics.
|Westesson, Oscar; Skinner, Mitchell; Holmes, Ian (2013) Visualizing next-generation sequencing data with JBrowse. Brief Bioinform 14:172-7|
|De Maio, Nicola; Holmes, Ian; Schlotterer, Christian et al. (2013) Estimating empirical codon hidden Markov models. Mol Biol Evol 30:725-36|
|Skinner, Mitchell E; Holmes, Ian H (2010) Setting up the JBrowse genome browser. Curr Protoc Bioinformatics Chapter 9:Unit 9.13|
|Skinner, Mitchell E; Uzilov, Andrew V; Stein, Lincoln D et al. (2009) JBrowse: a next-generation genome browser. Genome Res 19:1630-8|