Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL051014-03
Application #
2227380
Study Section
Pathology B Study Section (PTHB)
Project Start
1994-01-01
Project End
1996-12-31
Budget Start
1996-01-01
Budget End
1996-12-31
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Yale University
Department
Pathology
Type
Schools of Medicine
DUNS #
082359691
City
New Haven
State
CT
Country
United States
Zip Code
06520
Pellowe, Amanda S; Sauler, Maor; Hou, Yue et al. (2018) Endothelial cell-secreted MIF reduces pericyte contractility and enhances neutrophil extravasation. FASEB J :fj201800480R
Lim, Sangho; Kirkiles-Smith, Nancy C; Pober, Jordan S et al. (2018) Regulation of human T cell responses by dNP2-ctCTLA-4 inhibits human skin and microvessel graft rejection. Biomaterials 183:128-138
Liu, Rebecca; Merola, Jonathan; Manes, Thomas D et al. (2018) Interferon-? converts human microvascular pericytes into negative regulators of alloimmunity through induction of indoleamine 2,3-dioxygenase 1. JCI Insight 3:
Manes, Thomas D; Wang, Vivian; Pober, Jordan S (2018) Divergent TCR-Initiated Calcium Signals Govern Recruitment versus Activation of Human Alloreactive Effector Memory T Cells by Endothelial Cells. J Immunol 201:3167-3174
Pober, Jordan S; Merola, Jonathan; Liu, Rebecca et al. (2017) Antigen Presentation by Vascular Cells. Front Immunol 8:1907
Merola, Jonathan; Jane-Wit, Daniel D; Pober, Jordan S (2017) Recent advances in allograft vasculopathy. Curr Opin Organ Transplant 22:1-7
Lauridsen, Holly M; Pellowe, Amanda S; Ramanathan, Anand et al. (2017) Tumor Necrosis Factor-? and IL-17A Activation Induces Pericyte-Mediated Basement Membrane Remodeling in Human Neutrophilic Dermatoses. Am J Pathol 187:1893-1906
Abrahimi, Parwiz; Qin, Lingfeng; Chang, William G et al. (2016) Blocking MHC class II on human endothelium mitigates acute rejection. JCI Insight 1:
Liu, Rebecca; Lauridsen, Holly M; Amezquita, Robert A et al. (2016) IL-17 Promotes Neutrophil-Mediated Immunity by Activating Microvascular Pericytes and Not Endothelium. J Immunol 197:2400-8
Manes, Thomas D; Pober, Jordan S (2016) Significant Differences in Antigen-Induced Transendothelial Migration of Human CD8 and CD4 T Effector Memory Cells. Arterioscler Thromb Vasc Biol 36:1910-8

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