Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL073760-02
Application #
6767597
Study Section
Special Emphasis Panel (ZHL1-CSR-J (M2))
Program Officer
Thomas, John
Project Start
2003-07-01
Project End
2007-06-30
Budget Start
2004-07-01
Budget End
2005-06-30
Support Year
2
Fiscal Year
2004
Total Cost
$470,874
Indirect Cost

  Institution

Name
Mount Sinai School of Medicine
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
078861598
City
New York
State
NY
Country
United States
Zip Code
10029

  Publications

Luchsinger, Larry L; de Almeida, Mariana Justino; Corrigan, David J et al. (2016) Mitofusin 2 maintains haematopoietic stem cells with extensive lymphoid potential. Nature 529:528-31
Kamezaki, Kenjiro; Luchsinger, Larry L; Snoeck, Hans-Willem (2014) Differential requirement for wild-type Flt3 in leukemia initiation among mouse models of human leukemia. Exp Hematol 42:192-203.e1
Baker, Stacey J; Ma'ayan, Avi; Lieu, Yen K et al. (2014) B-myb is an essential regulator of hematopoietic stem cell and myeloid progenitor cell development. Proc Natl Acad Sci U S A 111:3122-7
Avagyan, Serine; Aguilo, Francesca; Kamezaki, Kenjiro et al. (2011) Quantitative trait mapping reveals a regulatory axis involving peroxisome proliferator-activated receptors, PRDM16, transforming growth factor-*2 and FLT3 in hematopoiesis. Blood 118:6078-86
Aguilo, Francesca; Avagyan, Serine; Labar, Amy et al. (2011) Prdm16 is a physiologic regulator of hematopoietic stem cells. Blood 117:5057-66
Kumar, Ritu; Avagyan, Serine; Snoeck, Hans-Willem (2010) A quantitative trait locus on chr.4 regulates thymic involution. J Gerontol A Biol Sci Med Sci 65:620-5
Avagyan, Serine; Glouchkova, Ludmila; Choi, Juhyun et al. (2008) A quantitative trait locus on chromosome 4 affects cycling of hematopoietic stem and progenitor cells through regulation of TGF-beta 2 responsiveness. J Immunol 181:5904-11
Kumar, Ritu; Langer, Jessica C; Snoeck, Hans-Willem (2006) Transforming growth factor-beta2 is involved in quantitative genetic variation in thymic involution. Blood 107:1974-9
Langer, Jessica C; Kumar, Ritu; Snoeck, Hans-Willem (2006) Age-related accumulation of a novel CD44 + CD25lowgammadelta T-cell population in hematopoietic organs of the mouse. J Gerontol A Biol Sci Med Sci 61:568-71
Henckaerts, Els; Langer, Jessica C; Orenstein, Jonathan et al. (2004) The positive regulatory effect of TGF-beta2 on primitive murine hemopoietic stem and progenitor cells is dependent on age, genetic background, and serum factors. J Immunol 173:2486-93