The overall aim of the current revised (third submission) proposal is to develop knowledge about the prevention of panic attacks and panic disorder (PD) using a specialized anxiety-smoking cessation intervention. This program will target, within the context of a controlled prevention program, two malleable vulnerability factors for the development of PD - anxiety sensitivity (the fear of anxiety and anxiety-related sensations) and cigarette smoking. The prevention program, implemented across two sites, will utilize cognitive restructuring and interoceptive exposure strategies with a specific focus on reducing the fear of anxiety in order to (1) decrease the development of panic attacks and panic disorder; and (2) facilitate successful cessation. Both panic and smoking factors are of primary theoretical interest to an integrative intervention that seeks to modify risk processes relevant to both outcomes. It is noteworthy that this """"""""dual"""""""" focus has been recommended as an ideal strategy by the Institute of Medicine report on prevention science (Mrazek & Haggerty, 1994) as well as the recent NIMH Workgroup on Tobacco Use and Cessation in Psychiatric Disorders (Riley, 2005) for comorbid problems. Specifically, this Panic-Smoking Program (PSP) will integrate interoceptive exposure, cognitive restructuring, and psychoeducation exercises developed for panic prevention and treatment programs with standard smoking cessation counseling. To address the efficacy of the anxiety-related components of PSP, the program will be compared to a program consisting only of the smoking-related components of PSP (SP). This approach is aimed at establishing the efficacy of the PSP intervention relative to a contemporary smoking-cessation program. The primary aims focus on examining the effects of reductions in a psychological vulnerability factor (anxiety sensitivity) and a behavioral risk factor (smoking) in an integrated smoking-panic program designed to decrease the development of panic psychopathology and to facilitate smoking cessation. ? ? ?

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Research Project (R01)
Project #
5R01MH076629-02
Application #
7369806
Study Section
Adult Psychopathology and Disorders of Aging Study Section (APDA)
Program Officer
Muehrer, Peter R
Project Start
2007-04-01
Project End
2012-03-31
Budget Start
2008-04-01
Budget End
2009-03-31
Support Year
2
Fiscal Year
2008
Total Cost
$607,261
Indirect Cost
Name
University of Vermont & St Agric College
Department
Psychology
Type
Schools of Arts and Sciences
DUNS #
066811191
City
Burlington
State
VT
Country
United States
Zip Code
05405
Garey, Lorra; Kauffman, Brooke Y; Manning, Kara F et al. (2018) The Effect of Positive and Negative Affect on Early Treatment Milestones in the Context of Integrated Smoking Treatment. J Addict Med :
Bakhshaie, Jafar; Kulesz, Paulina A; Garey, Lorra et al. (2018) A prospective investigation of the synergistic effect of change in anxiety sensitivity and dysphoria on tobacco withdrawal. J Consult Clin Psychol 86:69-80
Guillot, Casey R; Blumenthal, Heidemarie; Zvolensky, Michael J et al. (2018) Anxiety sensitivity components in relation to alcohol and cannabis use, motives, and problems in treatment-seeking cigarette smokers. Addict Behav 82:166-173
Kauffman, Brooke Y; Garey, Lorra; Jardin, Charles et al. (2018) Body Mass Index and functional impairment: the explanatory role of anxiety sensitivity among treatment-seeking smokers. Psychol Health Med 23:232-243
Rogers, Andrew H; Bakhshaie, Jafar; Garey, Lorra et al. (2018) Individual differences in emotion dysregulation and trajectory of withdrawal symptoms during a quit attempt among treatment-seeking smokers. Behav Res Ther :
Zvolensky, Michael J; Garey, Lorra; Fergus, Thomas A et al. (2018) Refinement of anxiety sensitivity measurement: The Short Scale Anxiety Sensitivity Index (SSASI). Psychiatry Res 269:549-557
Garey, Lorra; Peraza, Natalia; Smit, Tanya et al. (2018) Sex differences in smoking constructs and abstinence: The explanatory role of smoking outcome expectancies. Psychol Addict Behav 32:660-669
Albanese, Brian J; Macatee, Richard J; Boffa, Joseph W et al. (2018) Interactive effects of traumatic brain injury and anxiety sensitivity on PTSD symptoms: A replication and extension in two clinical samples. Cognit Ther Res 42:510-523
Zvolensky, Michael J; Garey, Lorra; Allan, Nicolas P et al. (2018) Effects of anxiety sensitivity reduction on smoking abstinence: An analysis from a panic prevention program. J Consult Clin Psychol 86:474-485
Garey, Lorra; Manning, Kara; Jardin, Charles et al. (2018) Smoking Consequences Questionnaire: A reevaluation of the psychometric properties across two independent samples of smokers. Psychol Assess 30:678-692

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