The overall aim of the current revised (third submission) proposal is to develop knowledge about the prevention of panic attacks and panic disorder (PD) using a specialized anxiety-smoking cessation intervention. This program will target, within the context of a controlled prevention program, two malleable vulnerability factors for the development of PD - anxiety sensitivity (the fear of anxiety and anxiety-related sensations) and cigarette smoking. The prevention program, implemented across two sites, will utilize cognitive restructuring and interoceptive exposure strategies with a specific focus on reducing the fear of anxiety in order to (1) decrease the development of panic attacks and panic disorder;and (2) facilitate successful cessation. Both panic and smoking factors are of primary theoretical interest to an integrative intervention that seeks to modify risk processes relevant to both outcomes. It is noteworthy that this """"""""dual"""""""" focus has been recommended as an ideal strategy by the Institute of Medicine report on prevention science (Mrazek &Haggerty, 1994) as well as the recent NIMH Workgroup on Tobacco Use and Cessation in Psychiatric Disorders (Riley, 2005) for comorbid problems. Specifically, this Panic-Smoking Program (PSP) will integrate interoceptive exposure, cognitive restructuring, and psychoeducation exercises developed for panic prevention and treatment programs with standard smoking cessation counseling. To address the efficacy of the anxiety-related components of PSP, the program will be compared to a program consisting only of the smoking-related components of PSP (SP). This approach is aimed at establishing the efficacy of the PSP intervention relative to a contemporary smoking-cessation program. The primary aims focus on examining the effects of reductions in a psychological vulnerability factor (anxiety sensitivity) and a behavioral risk factor (smoking) in an integrated smoking-panic program designed to decrease the development of panic psychopathology and to facilitate smoking cessation.

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Research Project (R01)
Project #
5R01MH076629-04
Application #
7798090
Study Section
Adult Psychopathology and Disorders of Aging Study Section (APDA)
Program Officer
Muehrer, Peter R
Project Start
2007-04-01
Project End
2012-03-31
Budget Start
2010-04-01
Budget End
2011-03-31
Support Year
4
Fiscal Year
2010
Total Cost
$585,719
Indirect Cost
Name
University of Vermont & St Agric College
Department
Psychology
Type
Schools of Arts and Sciences
DUNS #
066811191
City
Burlington
State
VT
Country
United States
Zip Code
05405
Garey, Lorra; Manning, Kara; Jardin, Charles et al. (2017) Smoking Consequences Questionnaire: A Reevaluation of the Psychometric Properties Across Two Independent Samples of Smokers. Psychol Assess :
Paulus, Daniel J; Valadka, Jaclyn; Businelle, Michael S et al. (2017) Emotion dysregulation explains associations between anxiety sensitivity and hazardous drinking and drinking motives among adult treatment-seeking smokers. Psychol Addict Behav 31:189-199
Short, Nicole A; Mathes, Brittany M; Gibby, Brittany et al. (2017) Insomnia symptoms as a risk factor for cessation failure following smoking treatment. Addict Res Theory 25:17-23
Garey, Lorra; Jardin, Charles; Kauffman, Brooke Y et al. (2017) Psychometric evaluation of the Barriers to Cessation Scale. Psychol Assess 29:844-856
Garey, Lorra; Taha, Samar A; Kauffman, Brooke Y et al. (2017) Treatment non-response: Associations with smoking expectancies among treatment-seeking smokers. Addict Behav 73:172-177
Garey, Lorra; Farris, Samantha G; Schmidt, Norman B et al. (2016) The Role of Smoking-Specific Experiential Avoidance in the Relation Between Perceived Stress and Tobacco Dependence, Perceived Barriers to Cessation, and Problems during Quit Attempts Among Treatment-Seeking Smokers. J Contextual Behav Sci 5:58-63
Garey, Lorra; Kauffman, Brooke Y; Neighbors, Clayton et al. (2016) Treatment attrition: Associations with negative affect smoking motives and barriers to quitting among treatment-seeking smokers. Addict Behav 63:165-71
Garey, Lorra; Bakhshaie, Jafar; Vujanovic, Anka A et al. (2016) Posttraumatic stress symptom severity and cognitive-based smoking processes among trauma-exposed treatment-seeking smokers: The role of perceived stress. Addict Behav 60:84-9
Schmidt, Norman B; Raines, Amanda M; Allan, Nicholas P et al. (2016) Anxiety sensitivity risk reduction in smokers: A randomized control trial examining effects on panic. Behav Res Ther 77:138-46
Farris, Samantha G; DiBello, Angelo M; Heggeness, Luke F et al. (2016) Sustained smoking abstinence is associated with reductions in smoking-specific experiential avoidance among treatment-seeking smokers. J Behav Ther Exp Psychiatry 51:51-7

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