One of the fundamental cognitive components of all social exchange is reciprocity - the concept that a social gesture by one agent should be answered by a roughly equivalent gesture from the other agent. Despite the importance of reciprocity as a fundamental cognitive mechanism, our neural and behavioral understanding of reciprocity instincts in humans remains rudimentary. The overall goal of this proposal is to probe reciprocity across a variety of two- agent settings, expose its influence on behavioral responses during such staged social exchange, and generate mathematical data-driven descriptions of its computational components. In all cases, we seek to relate behavioral variables involved in reciprocal interaction between two agents to underlying neural correlates as measured by functional magnetic resonance imaging (fMRI). We make liberal use of economic exchange games commonly employed in behavioral economics.
The fundamental brain and cognitive mechanisms underlying social interactions among humans are almost completely unknown. This tremendous gap in our knowledge is made worse by the fact that many forms of mental illness and brain injury severely impair our capacity to sustain normal cooperative interactions with other humans. This proposal will use functional magnetic resonance imaging, staged social interactions, and computational theory to probe the way that humans carry out reciprocal social exchange.
|Hétu, Sébastien; Luo, Yi; Saez, Ignacio et al. (2016) Asymmetry in functional connectivity of the human habenula revealed by high-resolution cardiac-gated resting state imaging. Hum Brain Mapp 37:2602-15|
|Lu, James; Kishida, Ken; De Asis Cruz, Josepheen et al. (2015) Single stimulus fMRI produces a neural individual difference measure for Autism Spectrum Disorder. Clin Psychol Sci 3:422-432|
|Gu, Xiaosi; Lohrenz, Terry; Salas, Ramiro et al. (2015) Belief about nicotine selectively modulates value and reward prediction error signals in smokers. Proc Natl Acad Sci U S A 112:2539-44|
|Hula, Andreas; Montague, P Read; Dayan, Peter (2015) Monte Carlo Planning Method Estimates Planning Horizons during Interactive Social Exchange. PLoS Comput Biol 11:e1004254|
|Kirk, Ulrich; Brown, Kirk Warren; Downar, Jonathan (2015) Adaptive neural reward processing during anticipation and receipt of monetary rewards in mindfulness meditators. Soc Cogn Affect Neurosci 10:752-9|
|Kirk, Ulrich; Montague, P Read (2015) Mindfulness meditation modulates reward prediction errors in a passive conditioning task. Front Psychol 6:90|
|Gu, Xiaosi; Kirk, Ulrich; Lohrenz, Terry M et al. (2014) Cognitive strategies regulate fictive, but not reward prediction error signals in a sequential investment task. Hum Brain Mapp 35:3738-49|
|Smith, Alec; Lohrenz, Terry; King, Justin et al. (2014) Irrational exuberance and neural crash warning signals during endogenous experimental market bubbles. Proc Natl Acad Sci U S A 111:10503-8|
|Kishida, Kenneth T; Montague, P Read (2013) Economic probes of mental function and the extraction of computational phenotypes. J Econ Behav Organ 94:234-241|
|Xiang, Ting; Lohrenz, Terry; Montague, P Read (2013) Computational substrates of norms and their violations during social exchange. J Neurosci 33:1099-108a|
Showing the most recent 10 out of 24 publications