Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
5R01NS022475-08
Application #
2264523
Study Section
Neurology C Study Section (NEUC)
Project Start
1985-09-23
Project End
1998-01-31
Budget Start
1996-02-01
Budget End
1997-01-31
Support Year
8
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Wisconsin Madison
Department
Pathology
Type
Schools of Veterinary Medicine
DUNS #
161202122
City
Madison
State
WI
Country
United States
Zip Code
53715
Messing, Albee; Brenner, Michael; Feany, Mel B et al. (2012) Alexander disease. J Neurosci 32:5017-23
Messing, Albee; Li, Rong; Naidu, Sakkubai et al. (2012) Archetypal and new families with Alexander disease and novel mutations in GFAP. Arch Neurol 69:208-14
Hagemann, Tracy L; Gaeta, Stephen A; Smith, Mark A et al. (2005) Gene expression analysis in mice with elevated glial fibrillary acidic protein and Rosenthal fibers reveals a stress response followed by glial activation and neuronal dysfunction. Hum Mol Genet 14:2443-58
van der Knaap, Marjo S; Salomons, Gajja S; Li, Rong et al. (2005) Unusual variants of Alexander's disease. Ann Neurol 57:327-38
Su, Mu; Hu, Huimin; Lee, Youngjin et al. (2004) Expression specificity of GFAP transgenes. Neurochem Res 29:2075-93
Messing, Albee; Brenner, Michael (2003) GFAP: functional implications gleaned from studies of genetically engineered mice. Glia 43:87-90
Lesche, Ralf; Groszer, Matthias; Gao, Jing et al. (2002) Cre/loxP-mediated inactivation of the murine Pten tumor suppressor gene. Genesis 32:148-9
Li, Rong; Messing, Albee; Goldman, James E et al. (2002) GFAP mutations in Alexander disease. Int J Dev Neurosci 20:259-68
Gorospe, J R; Naidu, S; Johnson, A B et al. (2002) Molecular findings in symptomatic and pre-symptomatic Alexander disease patients. Neurology 58:1494-500
Zhuo, L; Theis, M; Alvarez-Maya, I et al. (2001) hGFAP-cre transgenic mice for manipulation of glial and neuronal function in vivo. Genesis 31:85-94

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