Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
5R01NS025372-09
Application #
2265539
Study Section
Neurology A Study Section (NEUA)
Project Start
1988-02-01
Project End
1997-01-31
Budget Start
1996-02-01
Budget End
1997-01-31
Support Year
9
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of California San Francisco
Department
Neurosurgery
Type
Schools of Medicine
DUNS #
073133571
City
San Francisco
State
CA
Country
United States
Zip Code
94143
Wakai, Takuma; Narasimhan, Purnima; Sakata, Hiroyuki et al. (2016) Hypoxic preconditioning enhances neural stem cell transplantation therapy after intracerebral hemorrhage in mice. J Cereb Blood Flow Metab 36:2134-2145
Wakai, Takuma; Sakata, Hiroyuki; Narasimhan, Purnima et al. (2014) Transplantation of neural stem cells that overexpress SOD1 enhances amelioration of intracerebral hemorrhage in mice. J Cereb Blood Flow Metab 34:441-9
Okami, Nobuya; Narasimhan, Purnima; Yoshioka, Hideyuki et al. (2013) Prevention of JNK phosphorylation as a mechanism for rosiglitazone in neuroprotection after transient cerebral ischemia: activation of dual specificity phosphatase. J Cereb Blood Flow Metab 33:106-14
Yang, Jiwon; Ahn, Hye-Na; Chang, Minsun et al. (2013) Complement component 3 inhibition by an antioxidant is neuroprotective after cerebral ischemia and reperfusion in mice. J Neurochem 124:523-35
Yoshioka, Hideyuki; Katsu, Masataka; Sakata, Hiroyuki et al. (2013) The role of PARL and HtrA2 in striatal neuronal injury after transient global cerebral ischemia. J Cereb Blood Flow Metab 33:1658-65
Sakata, Hiroyuki; Niizuma, Kuniyasu; Yoshioka, Hideyuki et al. (2012) Minocycline-preconditioned neural stem cells enhance neuroprotection after ischemic stroke in rats. J Neurosci 32:3462-73
Kim, Gab Seok; Jung, Joo Eun; Narasimhan, Purnima et al. (2012) Release of mitochondrial apoptogenic factors and cell death are mediated by CK2 and NADPH oxidase. J Cereb Blood Flow Metab 32:720-30
Nito, Chikako; Kamada, Hiroshi; Endo, Hidenori et al. (2012) Involvement of mitogen-activated protein kinase pathways in expression of the water channel protein aquaporin-4 after ischemia in rat cortical astrocytes. J Neurotrauma 29:2404-12
Sakata, Hiroyuki; Narasimhan, Purnima; Niizuma, Kuniyasu et al. (2012) Interleukin 6-preconditioned neural stem cells reduce ischaemic injury in stroke mice. Brain 135:3298-310
Sakata, Hiroyuki; Niizuma, Kuniyasu; Wakai, Takuma et al. (2012) Neural stem cells genetically modified to overexpress cu/zn-superoxide dismutase enhance amelioration of ischemic stroke in mice. Stroke 43:2423-9

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