Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
5R01NS034151-03
Application #
2609683
Study Section
Neurological Sciences Subcommittee 1 (NLS)
Program Officer
Jacobs, Margaret
Project Start
1995-12-13
Project End
1998-11-30
Budget Start
1997-12-01
Budget End
1998-11-30
Support Year
3
Fiscal Year
1998
Total Cost
Indirect Cost
Name
Weill Medical College of Cornell University
Department
Pharmacology
Type
Schools of Medicine
DUNS #
201373169
City
New York
State
NY
Country
United States
Zip Code
10065
Yun, Seong-Wook; Platholi, Jimcy; Flaherty, Maria Sol et al. (2006) Fmrp is required for the establishment of the startle response during the critical period of auditory development. Brain Res 1110:159-65
Liu, Wencheng; Seto, Jeremy; Sibille, Etienne et al. (2003) The RNA binding domain of Jerky consists of tandemly arranged helix-turn-helix/homeodomain-like motifs and binds specific sets of mRNAs. Mol Cell Biol 23:4083-93
Chen, L; Yun, S W; Seto, J et al. (2003) The fragile X mental retardation protein binds and regulates a novel class of mRNAs containing U rich target sequences. Neuroscience 120:1005-17
Toth, Miklos (2003) 5-HT1A receptor knockout mouse as a genetic model of anxiety. Eur J Pharmacol 463:177-84
Liu, Wencheng; Seto, Jeremy; Donovan, Gerald et al. (2002) Jerky, a protein deficient in a mouse epilepsy model, is associated with translationally inactive mRNA in neurons. J Neurosci 22:176-82
Chen, L; Toth, M (2001) Fragile X mice develop sensory hyperreactivity to auditory stimuli. Neuroscience 103:1043-50
Wood, S J; Toth, M (2001) Molecular pathways of anxiety revealed by knockout mice. Mol Neurobiol 23:101-19
Sarnyai, Z; Sibille, E L; Pavlides, C et al. (2000) Impaired hippocampal-dependent learning and functional abnormalities in the hippocampus in mice lacking serotonin(1A) receptors. Proc Natl Acad Sci U S A 97:14731-6
Toth, M; Tecott, L (1999) Transgenic approaches to epilepsy. Adv Neurol 79:291-6
Donovan, G P; Harden, C; Gal, J et al. (1997) Sensitivity to jerky gene dosage underlies epileptic seizures in mice. J Neurosci 17:4562-9