Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
9R01NS041966-06A1
Application #
6326327
Study Section
Integrative, Functional and Cognitive Neuroscience 8 (IFCN)
Program Officer
Edwards, Emmeline
Project Start
1995-09-30
Project End
2006-04-30
Budget Start
2001-05-01
Budget End
2002-04-30
Support Year
6
Fiscal Year
2001
Total Cost
$348,289
Indirect Cost
Name
State University New York Stony Brook
Department
Other Basic Sciences
Type
Schools of Arts and Sciences
DUNS #
804878247
City
Stony Brook
State
NY
Country
United States
Zip Code
11794
Locklear, Mallory N; Michaelos, Michalis; Collins, William F et al. (2017) Gonadectomy but not biological sex affects burst-firing in dopamine neurons of the ventral tegmental area and in prefrontal cortical neurons projecting to the ventral tegmentum in adult rats. Eur J Neurosci 45:106-120
Locklear, M N; Cohen, A B; Jone, A et al. (2016) Sex Differences Distinguish Intracortical Glutamate Receptor-Mediated Regulation of Extracellular Dopamine Levels in the Prefrontal Cortex of Adult Rats. Cereb Cortex 26:599-610
Locklear, M N; Bhamidipaty, S; Kritzer, M F (2015) Local N-methyl-d-aspartate receptor antagonism in the prefrontal cortex attenuates spatial cognitive deficits induced by gonadectomy in adult male rats. Neuroscience 288:73-85
Locklear, M N; Kritzer, M F (2014) Assessment of the effects of sex and sex hormones on spatial cognition in adult rats using the Barnes maze. Horm Behav 66:298-308
Feinstein, I; Kritzer, M F (2013) Acute N-methyl-D-aspartate receptor hypofunction induced by MK801 evokes sex-specific changes in behaviors observed in open-field testing in adult male and proestrus female rats. Neuroscience 228:200-14
Aubele, T; Kritzer, M F (2012) Androgen influence on prefrontal dopamine systems in adult male rats: localization of cognate intracellular receptors in medial prefrontal projections to the ventral tegmental area and effects of gonadectomy and hormone replacement on glutamate-stimulated Cereb Cortex 22:1799-812
Aubele, T; Kritzer, M F (2011) Gonadectomy and hormone replacement affects in vivo basal extracellular dopamine levels in the prefrontal cortex but not motor cortex of adult male rats. Cereb Cortex 21:222-32
Meyers, B; D'Agostino, A; Walker, J et al. (2010) Gonadectomy and hormone replacement exert region- and enzyme isoform-specific effects on monoamine oxidase and catechol-O-methyltransferase activity in prefrontal cortex and neostriatum of adult male rats. Neuroscience 165:850-62
Meyers, B; Kritzer, M F (2009) In vitro binding assays using (3)H nisoxetine and (3)H WIN 35,428 reveal selective effects of gonadectomy and hormone replacement in adult male rats on norepinephrine but not dopamine transporter sites in the cerebral cortex. Neuroscience 159:271-82
Kritzer, Mary F; Creutz, Lela M (2008) Region and sex differences in constituent dopamine neurons and immunoreactivity for intracellular estrogen and androgen receptors in mesocortical projections in rats. J Neurosci 28:9525-35

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