Fetotoxicity of Tcdd, Endrin and Lindane in Mice

Hassoun, Ezdihar A.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Environmental Health Sciences (NIEHS)
• Type: Academic Research Enhancement Awards (AREA) (R15)
• Project #: 7R15ES006818-02
• Application #: 2155719
• Study Section: Toxicology Subcommittee 2 (TOX)
• Project Start: 1994-06-01
• Project End: 1997-05-31
• Budget Start: 1995-10-17
• Budget End: 1997-05-31
• Support Year: 2
• Fiscal Year: 1994

Institution

• Name: University of Toledo
• Department: Pharmacology
• Type: Schools of Pharmacy
• City: Toledo
• State: OH
• Country: United States
• Zip Code: 43606

Publications

Hassoun, E A; Walter, A C; Alsharif, N Z et al. (1997) Modulation of TCDD-induced fetotoxicity and oxidative stress in embryonic and placental tissues of C57BL/6J mice by vitamin E succinate and ellagic acid. Toxicology 124:27-37

Hassoun, E A; Stohs, S J (1996) TCDD, endrin and lindane induced oxidative stress in fetal and placental tissues of C57BL/6J and DBA/2J mice. Comp Biochem Physiol C Pharmacol Toxicol Endocrinol 115:11-8

Hassoun, E A; Stohs, S J (1996) Comparative teratological studies on TCDD, endrin and lindane in C57BL/6J and DBA/2J mice. Comp Biochem Physiol C Pharmacol Toxicol Endocrinol 113:393-8

Hassoun, E A; Bagchi, D; Stohs, S J (1996) TCDD endrin and lindane induced increases in lipid metabolites in maternal sera and amniotic fluids of pregnant C57BL/6J and DBA/2J mice. Res Commun Mol Pathol Pharmacol 94:157-69

Hassoun, E A; Bagchi, D; Stohs, S J (1995) Evidence of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-induced tissue damage in fetal and placental tissues and changes in amniotic fluid lipid metabolites of pregnant CF1 mice. Toxicol Lett 76:245-50