Influenza vaccination protects individuals against infection, reduces absenteeism at work and missed days of school. The 2004-2005 flu season saw a substantial reduction in influenza vaccination rates due to a shortage in the supply of the influenza vaccine. Due to failure of a Chiron production plant, compared to previous years, there was approximately a 31 million-dose shortage of the influenza vaccine and vaccination rates in the country dropped by nearly 25%. In this proposal we aim to take advantage of this natural experiment to estimate the effect of this reduction in vaccination supply on a variety of outcomes including health care utilization, mortality, work productivity and school absenteeism. Specifically, we take advantage of the fact that states that ordered vaccinations specifically from Chiron were more likely to experience a vaccine shortage than states that did not order their vaccinations from Chiron. Calculations of state level vaccination rates from the Behavioral Risk Factor Social Survey data indicate substantial cross-state variation in reductions in vaccination rates due to the shortage, with some states experiencing nearly a 40% reduction in vaccination rates while other states experienced little to no reduction. In the analyses, using unique data from the CDC on state vaccination orders specifically to Chiron, we first instrument for the reduction in state vaccination rates in the 2004-2005 flu season. We then estimate the impact of this reduction on state level measures of health care utilization, influenza mortality, work productivity and school attendance. Compared to previous work in this area, our study promises to provide comprehensive estimates of the effects of the vaccination on these outcomes since we are able to capture these outcomes for both vaccinated and unvaccinated individuals in these states. A more comprehensive accounting of the benefits of vaccination has the potential to affect policy maker decision making with respect to the utilization of the influenza vaccination to increase population health.

Public Health Relevance

The 2004-2005 influenza vaccine shortage leads to substantial declines in influenza vaccination rates. We propose to estimate the effect of this supply shock on health care utilization, health outcomes, work productivity and school attendance. Our proposed analyses will capture the impact of increasing vaccination rates on both the vaccinated and unvaccinated populations.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Exploratory/Developmental Grants (R21)
Project #
1R21AI103741-01
Application #
8428603
Study Section
Social Sciences and Population Studies Study Section (SSPS)
Program Officer
Salomon, Rachelle
Project Start
2013-02-01
Project End
2015-01-31
Budget Start
2013-02-01
Budget End
2014-01-31
Support Year
1
Fiscal Year
2013
Total Cost
$275,409
Indirect Cost
$125,409
Name
Rand Corporation
Department
Type
DUNS #
006914071
City
Santa Monica
State
CA
Country
United States
Zip Code
90401