Solutes are excluded from the region immediately adjacent to various gel and biological surfaces (Zheng and Pollack, 2003). The solute-exclusion zone is considerably larger than anticipated by conventional theories: nominally on the order of 100 mu/m or more. Preliminary NMR data support the interpretation that this zone is created by layers of less mobile water molecules building from the surface, and excluding solutes as in the case of ice. The resulting """"""""structured water"""""""" zone is therefore solute free.
The aim of this proposal is determine whether this solute-free zone bears relation to """"""""structured water"""""""" employed in various alternative health-care regimes. Thus, the effects of magnetic fields will be explored. Studies will be carried out to determine whether water subjected to magnetic fields excludes solutes as does the gel-based exclusion zone; and, whether the exclusion zone itself is impacted by the application of such fields. NMR studies will provide complementary tests of whether such water molecules are motionally restricted. Various commercially available """"""""structured water"""""""" products will be tested as above to determine whether indeed such water's physical properties are different from ordinary water. Finally, the effect of vigorous shaking, as routinely carried out during succession, will be tested. It will be of interest to determine whether such water is any more or less structured than ordinary control water. These are pilot studies designed to obtain preliminary data that may be useful for subsequent, more detailed investigations on the molecular basis of homeopathic procedures.

Agency
National Institute of Health (NIH)
Institute
National Center for Complementary & Alternative Medicine (NCCAM)
Type
Exploratory/Developmental Grants (R21)
Project #
1R21AT002362-01
Application #
6814567
Study Section
Special Emphasis Panel (ZAT1-DB (13))
Program Officer
Wong, Shan S
Project Start
2004-09-15
Project End
2006-05-31
Budget Start
2004-09-15
Budget End
2005-05-31
Support Year
1
Fiscal Year
2004
Total Cost
$189,500
Indirect Cost
Name
University of Washington
Department
Biomedical Engineering
Type
Schools of Engineering
DUNS #
605799469
City
Seattle
State
WA
Country
United States
Zip Code
98195
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Chai, B; Mahtani, A G; Pollack, G H (2012) UNEXPECTED PRESENCE OF SOLUTE-FREE ZONES AT METAL-WATER INTERFACES. Contemp Mater 3:1-12
Zhao, Qing; Coult, Jason; Pollack, Gerald H (2010) Long-range attraction in aqueous colloidal suspensions. Proc SPIE Int Soc Opt Eng 7376:73761C1-73761C13
Chai, Binghua; Pollack, Gerald H (2010) Solute-free interfacial zones in polar liquids. J Phys Chem B 114:5371-5
Chai, Binghua; Yoo, Hyok; Pollack, Gerald H (2009) Effect of radiant energy on near-surface water. J Phys Chem B 113:13953-8
Zhao, Qing; Ovchinnikova, Kate; Chai, Binghua et al. (2009) Role of proton gradients in the mechanism of osmosis. J Phys Chem B 113:10708-14
Chai, Bing-hua; Zheng, Jian-ming; Zhao, Qing et al. (2008) Spectroscopic studies of solutes in aqueous solution. J Phys Chem A 112:2242-7
Zhao, Qing; Zheng, Jianming; Chai, Binghua et al. (2008) Unexpected effect of light on colloidal crystal spacing. Langmuir 24:1750-5
Klyuzhin, Ivan; Symonds, Andrew; Magula, Jeffrey et al. (2008) New method of water purification based on the particle-exclusion phenomenon. Environ Sci Technol 42:6160-6
Zheng, Jian-Ming; Chin, Wei-Chun; Khijniak, Eugene et al. (2006) Surfaces and interfacial water: evidence that hydrophilic surfaces have long-range impact. Adv Colloid Interface Sci 127:19-27