Diabetes mellitus (DM) is now the sixth leading cause of death in the U.S., primarily due to cardiovascular (CV) complications. People with DM have a 2 to 4 times increased risk for heart disease. An increasing number of adolescents are diagnosed with DM, predisposing them to CV morbidity and mortality in early adulthood. Using a comparison group pretest-posttest design, the Primary Aim of this investigation is to determine the feasibility of conducting a novel personalized exercise prescription (PEP) intervention with 20 adolescents who have type 1 DM and 20 adolescents with type 2 DM. We will explore the influence of DM- specific family social support, exercise self-efficacy, and benefits and barriers to exercise on adherence to PEP. The Secondary Aim is to explore possible changes in physiological (i.e., cardiorespiratory fitness, heart rate variability, metabolic control, and lipid profile) and psychosocial (i.e., diabetes quality of life [QOL]) outcomes of the PEP intervention in adolescents with type 1 or type 2 DM. Long-term benefits of exercise for persons with DM include decreased risk factors for CV disease, improved well-being, and increased life expectancy. The current decline in physical activity during adolescence is problematic, particularly for those with DM, who have an added risk for future CV disease. The limited research available on the efficacy of exercise interventions with youths who have type 1 DM indicates improvements in cardiorespiratory fitness, lipid profile, and glucose regulation. No published exercise intervention research with adolescents who have type 2 DM is available. However, exercise interventions with overweight youth have shown increased heart rate variability and cardiorespiratory fitness. Although numerous studies have examined various school- based strategies to promote more physically active lives in youth populations, no studies have examined the feasibility of conducting individualized, culturally focused exercise prescriptions for adolescents with type 1 or type 2 DM that incorporate family support in a home or community setting. Nor have studies addressed the possible physiological and psychosocial outcomes of these personalized approaches. This investigation will extend the principal investigator's program of research that identified differences in CV risks for adolescents with type 1 vs. type 2 DM. Determining factors that influence the conduct and outcomes of individualized exercise interventions for adolescents with DM can potentially lead to the development of programs that promote adherence to exercise, avert complications, and improve QOL and overall health. Lay Description: This study aims to determine the likely benefits of a study that would use the novel techniques both of writing an exercise """"""""prescription"""""""" and of including the family and/or community in sticking to the exercise prescription by youths with diabetes, who often suffer eventual cardiovascular complications that might be lessened by the exercise. ? ? ? ?

Agency
National Institute of Health (NIH)
Institute
National Institute of Nursing Research (NINR)
Type
Exploratory/Developmental Grants (R21)
Project #
7R21NR009267-02
Application #
7287723
Study Section
Nursing Science: Children and Families Study Section (NSCF)
Program Officer
Mccloskey, Donna J
Project Start
2006-09-18
Project End
2010-07-31
Budget Start
2007-08-01
Budget End
2010-07-31
Support Year
2
Fiscal Year
2007
Total Cost
$164,018
Indirect Cost
Name
University of Arizona
Department
Type
DUNS #
806345617
City
Tucson
State
AZ
Country
United States
Zip Code
85721
Faulkner, Melissa Spezia; Michaliszyn, Sara Fleet; Hepworth, Joseph T et al. (2014) Personalized exercise for adolescents with diabetes or obesity. Biol Res Nurs 16:46-54
Faulkner, Melissa Spezia (2012) Intervention fidelity: ensuring application to practice for youth and families. J Spec Pediatr Nurs 17:33-40
Michaliszyn, Sara Fleet; Faulkner, Melissa Spezia (2010) Physical activity and sedentary behavior in adolescents with type 1 diabetes. Res Nurs Health 33:441-9
Faulkner, Melissa Spezia; Michaliszyn, Sara Fleet; Hepworth, Joseph T (2010) A personalized approach to exercise promotion in adolescents with type 1 diabetes. Pediatr Diabetes 11:166-74