The proposed training program will support an undergraduate summer research experience at an institution (the University of South Dakota) that enrolls a high percentage of first generation college students (over one third) from a primarily rural environment. This program addresses a critical need of promoting rigorous research education in areas related to substance abuse and mental health issues throughout the country, and will better prepare students in South Dakota for post-graduate careers in basic science or clinical research fields.

Public Health Relevance

The proposed training program is designed to facilitate the pipeline of young promising scientists in the field of substance abuse and mental health research. This is important given that substance abuse and related problems pose a significant social, health and financial burden within the U.S., and the treatment of substance abuse and dependence is often compounded by severe mental illness. Therefore, it is critical to increase the pool of quality, innovative and highly motivated scientists in the area of substance abuse in mental health research.

National Institute of Health (NIH)
National Institute on Drug Abuse (NIDA)
Education Projects (R25)
Project #
Application #
Study Section
Special Emphasis Panel (ZDA1)
Program Officer
Cotto, Jessica
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
University of South Dakota
Other Basic Sciences
Schools of Medicine
United States
Zip Code
Robertson, James M; Achua, Justin K; Smith, Justin P et al. (2017) Anxious behavior induces elevated hippocampal Cb2 receptor gene expression. Neuroscience 352:273-284
Summers, Torrie; Hanten, Brandon; Peterson, Warren et al. (2017) Endocannabinoids Have Opposing Effects On Behavioral Responses To Nociceptive And Non-nociceptive Stimuli. Sci Rep 7:5793
Watt, Michael J; Weber, Matthew A; Davies, Shaydel R et al. (2017) Impact of juvenile chronic stress on adult cortico-accumbal function: Implications for cognition and addiction. Prog Neuropsychopharmacol Biol Psychiatry 79:136-154
Ronan, Patrick J; Strait, Sydney A; Palmer, Geralyn M et al. (2017) Central Administration of Cyclosporine A Decreases Ethanol Drinking. Alcohol Alcohol :
Qiao, Fangfang; Longley, Kirsty R; Feng, Shelley et al. (2017) Reduced body weight gain in ubiquilin-1 transgenic mice is associated with increased expression of energy-sensing proteins. Physiol Rep 5:
Adegoke, Oludotun O; Qiao, Fangfang; Liu, Yanying et al. (2017) Overexpression of Ubiquilin-1 Alleviates Alzheimer's Disease-Caused Cognitive and Motor Deficits and Reduces Amyloid-? Accumulation in Mice. J Alzheimers Dis 59:575-590
Simons, Raluca M; Sistad, Rebecca E; Simons, Jeffrey S et al. (2017) The role of distress tolerance in the relationship between cognitive schemas and alcohol problems among college students. Addict Behav 78:1-8
Smith, Justin P; Prince, Melissa A; Achua, Justin K et al. (2016) Intensity of anxiety is modified via complex integrative stress circuitries. Psychoneuroendocrinology 63:351-61
Robertson, James M; Prince, Melissa A; Achua, Justin K et al. (2015) Nuance and behavioral cogency: How the Visible Burrow System inspired the Stress-Alternatives Model and conceptualization of the continuum of anxiety. Physiol Behav 146:86-97