The goal of the IMSD is to increase the numbers and success of underrepresented (UR) scientists (Ph.D. and MD/Ph.D.s) trained by the Graduate School of Baylor College of Medicine. $ 8.1 million in grants (1998-2014) provided educational opportunities to students to enhance UR participation and success in biomedical research careers. Since 1998, 89 UR students have earned PhDs, 12 of them MD/PhDs and 3 MDs after medical school. Currently, 87 of them are employed in science, with two others returning soon. Fifteen alumni have faculty positions at Tier 1 institutions (43% who have finished post-docs or residencies). They have acquired a few grants already, including a K99/00, an Early Independence, a R01, a Robert Wood Johnson, and 5 grants from other sources. Ten Ph.D. students are supported each year (salaries and fringe). UR graduate student education has been enhanced by creating individual development plans for each under-represented Ph.D. student with opportunities for a summer bridge program that sponsors a review of molecular and cellular biology, and a mini-review of genetics and neuroscience. Students have increased time to complete graduate coursework with tutoring support, faculty mentoring, fellowship application training, skills building workshops, including four tiers of writing workshops and scientific conference participation. Activities of the Association for Graduate Student Diversity have been enhanced;a seminar series features local and external minority scientists. The number of UR Ph.D. and MD/Ph.D. students enrolled at Baylor College of Medicine at any one time increased from 20 in 1998 to 38 in August of 2001 to 80 by August of 2007. The retention rate of UR Ph.D. students has risen from approximately 66% pre- IMSD to more than 85%. Since 1998, 89 under-represented minority students have received Ph.D.s and 10 received terminal M.S. degrees. The numbers of UR students receiving local, national and international awards has increased dramatically since 1998, to more than 220 awards, including 55 national fellowships. UR students now win research awards and fellowships at a higher rate than non-UR students (www.bcm.edu/diversityprogams). All alumni are progressing in their careers in science or professions where they use their scientific backgrounds.

Public Health Relevance

Each year, the BCM IMSD graduates more than 10 under-represented PhDs in biomedical sciences who go on to establish productive careers using their science backgrounds. They inspire others and serve as role models as they advance biomedical science.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Education Projects (R25)
Project #
2R25GM056929-17
Application #
8636256
Study Section
Special Emphasis Panel (TWD)
Program Officer
Janes, Daniel E
Project Start
1998-03-01
Project End
2019-01-31
Budget Start
2014-03-15
Budget End
2015-01-31
Support Year
17
Fiscal Year
2014
Total Cost
$288,862
Indirect Cost
$19,907
Name
Baylor College of Medicine
Department
Type
Schools of Medicine
DUNS #
051113330
City
Houston
State
TX
Country
United States
Zip Code
77030
Wang, Shang; Garcia, Monica D; Lopez 3rd, Andrew L et al. (2017) Dynamic imaging and quantitative analysis of cranial neural tube closure in the mouse embryo using optical coherence tomography. Biomed Opt Express 8:407-419
Palmieri, Michela; Pal, Rituraj; Nelvagal, Hemanth R et al. (2017) mTORC1-independent TFEB activation via Akt inhibition promotes cellular clearance in neurodegenerative storage diseases. Nat Commun 8:14338
Grau, Christina; Starkovich, Molly; Azamian, Mahshid S et al. (2017) Xp11.22 deletions encompassing CENPVL1, CENPVL2, MAGED1 and GSPT2 as a cause of syndromic X-linked intellectual disability. PLoS One 12:e0175962
Xie, Wei Rose; Jen, Hsin-I; Seymour, Michelle L et al. (2017) An Atoh1-S193A Phospho-Mutant Allele Causes Hearing Deficits and Motor Impairment. J Neurosci 37:8583-8594
Wang, Shang; Lakomy, David S; Garcia, Monica D et al. (2016) Four-dimensional live imaging of hemodynamics in mammalian embryonic heart with Doppler optical coherence tomography. J Biophotonics 9:837-47
Meng, Xiangling; Wang, Wei; Lu, Hui et al. (2016) Manipulations of MeCP2 in glutamatergic neurons highlight their contributions to Rett and other neurological disorders. Elife 5:
Yan, Chunling; He, Yanlin; Xu, Yuanzhong et al. (2016) Apolipoprotein A-IV Inhibits AgRP/NPY Neurons and Activates Pro-Opiomelanocortin Neurons in the Arcuate Nucleus. Neuroendocrinology 103:476-488
Herrera, José A; Ward, Christopher S; Wehrens, Xander H T et al. (2016) Methyl-CpG binding-protein 2 function in cholinergic neurons mediates cardiac arrhythmogenesis. Hum Mol Genet :
Herrera, José A; Ward, Christopher S; Wehrens, Xander H T et al. (2016) Methyl-CpG binding-protein 2 function in cholinergic neurons mediates cardiac arrhythmogenesis. Hum Mol Genet 25:4983-4995
Hinton Jr, Antentor Othrell; Yang, Yongjie; Quick, Ann P et al. (2016) SRC-1 Regulates Blood Pressure and Aortic Stiffness in Female Mice. PLoS One 11:e0168644

Showing the most recent 10 out of 61 publications