The overall aim of the SDSU Minority Biomedical Research Support Program (MBRS) IMSD program is to increase the number of students from underrepresented groups who attain Ph.D. degrees in the biomedical, behavioral and physical sciences. We will facilitate their exposure to science, academia and careers as researchers. The program will provide 20 undergraduates with faculty mentoring, customized advising, extracurricular experiences and opportunities for communicating with engaged peers each year during the course of the project period. We have assembled a dedicated group of active research mentors who will provide our students with hands-on research training. Our management and assessment plan will measure and ensure program and student success. We will provide a highly personalized experience to the students so that they can become the successful science leaders of tomorrow, and thereby, improve the diversity of academic scientists. Furthermore, we provide documentation of the effects our program has had upon students. Our training program will result in students with strong, highly competitive applications for doctoral programs such that at least 60% of our graduating seniors will directly enter into Ph.D. programs in the biomedical, behavioral and physical sciences. To accomplish this long-term goal, we plan to (1) implement a Pre-IMSD Biomedical Exploration Program (BEP) for freshman/sophomore students to introduce biomedical research and the pathway to preparing early for graduate school in the biomedical/behavioral sciences, (2) provide year-round mentored research experiences that will allow 20 IMSD undergraduate students to acquire excellent research and laboratory skills, and (3) develop the critical thinking and oral and writte communication skills of all program participants, by providing opportunities to present their research before professional audiences and to contribute to manuscripts for publication. We also propose three aims related to program evaluation: (1) to systematically measure program outcomes with mixed methods of quantitative and qualitative data collection and the establishment of a comprehensive electronic tracking database, (2) to use the data to continuously improve the program by maintaining elements that are most effective and modifying those that are least effective, and (3) to document the process of the SDSU IMSD program so that it becomes a model of accountability and to assure future success.

Public Health Relevance

The SDSU IMSD program is designed to train talented underrepresented students in science, technology, engineering and mathematics. A major goal of the program is to increase the diversity of the workforce in biomedical science, which will increase its capability and relieve the imbalance in health care and health care research. Ending health disparities is one of the top priorities for almost every federal, state and local health agency and was a major component of Healthy People 2010. Our IMSD students will be able use their scientific and leadership skills to help end health disparities through research and policy implementation.

National Institute of Health (NIH)
Education Projects (R25)
Project #
Application #
Study Section
Minority Programs Review Subcommittee B (MPRC)
Program Officer
Janes, Daniel E
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
San Diego State University
Schools of Arts and Sciences
San Diego
United States
Zip Code
Weerasinghe, Aruna J; Amin, Shady A; Barker, Ryan A et al. (2013) Borate as a synergistic anion for Marinobacter algicola ferric binding protein, FbpA: a role for boron in iron transport in marine life. J Am Chem Soc 135:14504-7
Romano, Ariel; Trimble, Lyndsay; Hobusch, Ashtian R et al. (2013) Regulation of iron transport related genes by boron in the marine bacterium Marinobacter algicola DG893. Metallomics 5:1025-30
Gardes, Astrid; Triana, Christopher; Amin, Shady A et al. (2013) Detection of photoactive siderophore biosynthetic genes in the marine environment. Biometals 26:507-16
Martinez, Suzanna M; Ayala, Guadalupe X; Patrick, Kevin et al. (2012) Associated pathways between neighborhood environment, community resource factors, and leisure-time physical activity among Mexican-American adults in San Diego, California. Am J Health Promot 26:281-8
Romano, Ariel A; Hahn, Tobias; Davis, Nicole et al. (2012) The Fe(III) and Ga(III) coordination chemistry of 3-(1-hydroxymethylidene) and 3-(1-hydroxydecylidene)-5-(2-hydroxyethyl)pyrrolidine-2,4-dione: novel tetramic acid degradation products of homoserine lactone bacterial quorum sensing molecules. J Inorg Biochem 107:96-103
Amin, Shady A; Green, David H; Gardes, Astrid et al. (2012) Siderophore-mediated iron uptake in two clades of Marinobacter spp. associated with phytoplankton: the role of light. Biometals 25:181-92
Zamora, R; Bartholow, J; Green, E et al. (2012) Adiposity measures predict olfactory processing speed in older adult carriers of the apolipoprotein E ýý4 allele. Clin Neurophysiol 123:918-24
Ruller, Chelsea M; Tabor-Godwin, Jenna M; Van Deren Jr, Donn A et al. (2012) Neural stem cell depletion and CNS developmental defects after enteroviral infection. Am J Pathol 180:1107-20
Huang, Chengqun; Andres, Allen M; Ratliff, Eric P et al. (2011) Preconditioning involves selective mitophagy mediated by Parkin and p62/SQSTM1. PLoS One 6:e20975
Sheen, Tamsin R; Jimenez, Alyssa; Wang, Nai-Yu et al. (2011) Serine-rich repeat proteins and pili promote Streptococcus agalactiae colonization of the vaginal tract. J Bacteriol 193:6834-42

Showing the most recent 10 out of 35 publications