With the over-representation of racial and ethnic minority (REM) populations in HIV/AIDS, there is a need to recruit and mentor REM scientists involved in neuroAIDS investigations. The Mount Sinai Institute for NeuroAIDS Disparities (MSINAD) will stimulate entry and retention of REM and non-REM scientists working in the field of neuroAIDS disparities. This institute offers a multi-disciplinary curriculum spanning the fields of neurology, neuropsychology, psychiatry, neuropathology, and neuroscience. Selected scholars are given both didactic seminars and a research practicum;didactics cover both topics germaine to neuroAIDS disorders, and general tools for academic success, including grant development. Scholars are matched with both a scientific and a development mentor, and have access to a multi-disciplinary panel of senior scientists as well as junior faculty in AIDS disparities research as role models. By summer's end, scholars gain a strong grounding in topics necessary to conduct high quality, multi- disciplinary translational neuroAIDS research in REM communities. The MSINAD builds upon the infrastructures of two programs. The Manhattan HIV Brain Bank is a multi-disciplinary research resource that maintains an HIV-positive REM cohort that undergoes longitudinal neurologic, neuropsychologic, and psychiatric assessments. It routinely interacts with and supports a variety of neuroscientists investigating HIV manifestations and neuropathogenesis, has conducted pilot analyses of neuroAIDS disparities, and has successfully recruited and trained minority investigators who are entering the neuroAIDS research work force. The Mount Sinai Center for Multicultural and Community Affairs is a Center of Excellence for Minority Health, focused on reducing REM health outcome disparities by developing increased health care work force diversity, and providing support services at a variety of educational training and practice levels. Its Faculty Development Programs support minorities in a variety of research and clinical career pathways. By combining the unique strengths of these two programs, the MSINAD creates high quality, REM researchers whose long term careers will make a lasting contribution to the area of neuroAIDS disparities.

Public Health Relevance

As HIV/AIDS disproportionately impacts minority communities, it is imperative to generate a research workforce capable of investigating HIV-related nervous system disorders in culturally and scientifically appropriate manners. MSINAD has been created to recruit, train, mentor, and support the talents of young scientists interested in neuroAIDS disparities research, with a focus on REM investigators. MSINAD programs seek to improve the quality of research into neuroAIDS disorders.

National Institute of Health (NIH)
National Institute of Mental Health (NIMH)
Education Projects (R25)
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Special Emphasis Panel (ZMH1-ERB-S (03))
Program Officer
Stoff, David M
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Icahn School of Medicine at Mount Sinai
Schools of Medicine
New York
United States
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Panos, Stella E; Del Re, A C; Thames, April D et al. (2014) The impact of neurobehavioral features on medication adherence in HIV: evidence from longitudinal models. AIDS Care 26:79-86
Gutierrez, Jose; Goldman, James; Honig, Lawrence S et al. (2014) Determinants of cerebrovascular remodeling: do large brain arteries accommodate stenosis? Atherosclerosis 235:371-9
Litvintseva, Anastasia P; Lindsley, Mark D; Gade, Lalitha et al. (2014) Utility of (1-3)-*-D-glucan testing for diagnostics and monitoring response to treatment during the multistate outbreak of fungal meningitis and other infections. Clin Infect Dis 58:622-30
Rubin, Leah H; Sundermann, Erin E; Cook, Judith A et al. (2014) Investigation of menopausal stage and symptoms on cognition in human immunodeficiency virus-infected women. Menopause 21:997-1006
Robbins, Reuben N; Brown, Henry; Ehlers, Andries et al. (2014) A Smartphone App to Screen for HIV-Related Neurocognitive Impairment. J Mob Technol Med 3:23-26
Lyons, Jennifer L; Coleman, Mary E; Engstrom, John W et al. (2014) International electives in neurology training: a survey of US and Canadian program directors. Neurology 82:119-25
Gutierrez, Jose; Rosoklija, Gorazd; Murray, Jacinta et al. (2014) A quantitative perspective to the study of brain arterial remodeling of donors with and without HIV in the Brain Arterial Remodeling Study (BARS). Front Physiol 5:56
Xu, Xiaomeng; Jerskey, Beth A; Cote, Denise M et al. (2014) Cerebrovascular perfusion among older adults is moderated by strength training and gender. Neurosci Lett 560:26-30
Jacobs, Michelle M; Murray, Jacinta; Byrd, Desiree A et al. (2013) HIV-related cognitive impairment shows bi-directional association with dopamine receptor DRD1 and DRD2 polymorphisms in substance-dependent and substance-independent populations. J Neurovirol 19:495-504
Robbins, Reuben N; Joska, John A; Thomas, Kevin G F et al. (2013) Exploring the utility of the Montreal Cognitive Assessment to detect HIV-associated neurocognitive disorder: the challenge and need for culturally valid screening tests in South Africa. Clin Neuropsychol 27:437-54

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