Agency
National Institute of Health (NIH)
Institute
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
5R29AA010384-02
Application #
2047007
Study Section
Biochemistry, Physiology and Medicine Subcommittee (ALCB)
Project Start
1995-08-01
Project End
2000-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Louisiana State University Hsc New Orleans
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
782627814
City
New Orleans
State
LA
Country
United States
Zip Code
70112
Wang, J; Cheung, A T; Kolls, J K et al. (2001) Effects of adenovirus-mediated liver-selective overexpression of protein tyrosine phosphatase-1b on insulin sensitivity in vivo. Diabetes Obes Metab 3:367-80
Forlow, S B; Schurr, J R; Kolls, J K et al. (2001) Increased granulopoiesis through interleukin-17 and granulocyte colony-stimulating factor in leukocyte adhesion molecule-deficient mice. Blood 98:3309-14
Cheung, A T; Wang, J; Ree, D et al. (2000) Tumor necrosis factor-alpha induces hepatic insulin resistance in obese Zucker (fa/fa) rats via interaction of leukocyte antigen-related tyrosine phosphatase with focal adhesion kinase. Diabetes 49:810-9
Zhang, Z; Kolls, J K; Oliver, P et al. (2000) Activation of tumor necrosis factor-alpha-converting enzyme-mediated ectodomain shedding by nitric oxide. J Biol Chem 275:15839-44
Cheung, A T; Ree, D; Kolls, J K et al. (1998) An in vivo model for elucidation of the mechanism of tumor necrosis factor-alpha (TNF-alpha)-induced insulin resistance: evidence for differential regulation of insulin signaling by TNF-alpha. Endocrinology 139:4928-35
Kolls, J K; Lei, D; Stoltz, D et al. (1998) Adenoviral-mediated interferon-gamma gene therapy augments pulmonary host defense of ethanol-treated rats. Alcohol Clin Exp Res 22:157-62
Schwarzenberger, P; Lei, D; Freeman, S M et al. (1998) Antitumor activity with the HSV-tk-gene-modified cell line PA-1-STK in malignant mesothelioma. Am J Respir Cell Mol Biol 19:333-7
Cheng, D Y; Kolls, J K; Lei, D et al. (1997) In vivo and in vitro gene transfer and expression in rat intestinal epithelial cells by E1-deleted adenoviral vector. Hum Gene Ther 8:755-64
Kolls, J K; Lei, D; Vazquez, C et al. (1997) Exacerbation of murine Pneumocystis carinii infection by adenoviral-mediated gene transfer of a TNF inhibitor. Am J Respir Cell Mol Biol 16:112-8
Lei, D; Lancaster Jr, J R; Joshi, M S et al. (1997) Activation of alveolar macrophages and lung host defenses using transfer of the interferon-gamma gene. Am J Physiol 272:L852-9

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