Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
5R29CA054430-04
Application #
2095952
Study Section
Immunological Sciences Study Section (IMS)
Project Start
1992-03-01
Project End
1995-08-31
Budget Start
1995-03-01
Budget End
1995-08-31
Support Year
4
Fiscal Year
1995
Total Cost
Indirect Cost
Name
University of Alabama Birmingham
Department
Microbiology/Immun/Virology
Type
Schools of Dentistry
DUNS #
004514360
City
Birmingham
State
AL
Country
United States
Zip Code
35294
van Ginkel, F W; McGhee, J R; Liu, C et al. (1997) Adenoviral gene delivery elicits distinct pulmonary-associated T helper cell responses to the vector and to its transgene. J Immunol 159:685-93
Pascual, D W; Coste, M; Boyaka, P N et al. (1997) Spontaneously hypertensive rat: cholera toxin converts suppression to immunity through a Th2 cell-IL-4 pathway. Am J Physiol 273:R1509-18
van Ginkel, F W; Pascual, D W (1996) Recognition of neurokinin 1 receptor (NK1-R): an antibody to a peptide sequence from the third extracellular region binds to brain NK1-R. J Neuroimmunol 67:49-58
Dong, J Y; Wang, D; Van Ginkel, F W et al. (1996) Systematic analysis of repeated gene delivery into animal lungs with a recombinant adenovirus vector. Hum Gene Ther 7:319-31
Van Ginkel, F W; Liu, C; Simecka, J W et al. (1995) Intratracheal gene delivery with adenoviral vector induces elevated systemic IgG and mucosal IgA antibodies to adenovirus and beta-galactosidase. Hum Gene Ther 6:895-903
Pascual, D W; Beagley, K W; Kiyono, H et al. (1995) Substance P promotes Peyer's patch and splenic B cell differentiation. Adv Exp Med Biol 371A:55-9
Wu, S; Pascual, D W; VanCott, J L et al. (1995) Immune responses to novel Escherichia coli and Salmonella typhimurium vectors that express colonization factor antigen I (CFA/I) of enterotoxigenic E. coli in the absence of the CFA/I positive regulator cfaR. Infect Immun 63:4933-8
Pascual, D W; Kiyono, H; McGhee, J R (1994) The enteric nervous and immune systems: interactions for mucosal immunity and inflammation. Immunomethods 5:56-72
Pascual, D W; Pascual, V H; Bost, K L et al. (1993) Nitric oxide mediates immune dysfunction in the spontaneously hypertensive rat. Hypertension 21:185-94
Pascual, D W; Bost, K L; Xu-Amano, J et al. (1992) The cytokine-like action of substance P upon B cell differentiation. Reg Immunol 4:100-4