Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Unknown (R35)
Project #
3R35CA042580-11S1
Application #
2090840
Study Section
Special Emphasis Panel (SRC (88))
Project Start
1986-07-01
Project End
2000-04-30
Budget Start
1996-05-01
Budget End
1997-04-30
Support Year
11
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Harvard University
Department
Microbiology/Immun/Virology
Type
Schools of Arts and Sciences
DUNS #
071723621
City
Cambridge
State
MA
Country
United States
Zip Code
02138
Ma, Sheng; Liu, Mei-Ann; Yuan, Yi-Lu O et al. (2003) The serum-inducible protein kinase Snk is a G1 phase polo-like kinase that is inhibited by the calcium- and integrin-binding protein CIB. Mol Cancer Res 1:376-84
Lin, C Y; Madsen, M L; Yarm, F R et al. (2000) Peripheral Golgi protein GRASP65 is a target of mitotic polo-like kinase (Plk) and Cdc2. Proc Natl Acad Sci U S A 97:12589-94
Song, S; Grenfell, T Z; Garfield, S et al. (2000) Essential function of the polo box of Cdc5 in subcellular localization and induction of cytokinetic structures. Mol Cell Biol 20:286-98
Gallina, A; Simoncini, L; Garbelli, S et al. (1999) Polo-like kinase 1 as a target for human cytomegalovirus pp65 lower matrix protein. J Virol 73:1468-78
Lee, K S; Song, S; Erikson, R L (1999) The polo-box-dependent induction of ectopic septal structures by a mammalian polo kinase, plk, in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 96:14360-5
Greulich, H; Erikson, R L (1998) An analysis of Mek1 signaling in cell proliferation and transformation. J Biol Chem 273:13280-8
Brott, B K; Pinsky, B A; Erikson, R L (1998) Nlk is a murine protein kinase related to Erk/MAP kinases and localized in the nucleus. Proc Natl Acad Sci U S A 95:963-8
Lee, K S; Grenfell, T Z; Yarm, F R et al. (1998) Mutation of the polo-box disrupts localization and mitotic functions of the mammalian polo kinase Plk. Proc Natl Acad Sci U S A 95:9301-6
Alessandrini, A; Brott, B K; Erikson, R L (1997) Differential expression of MEK1 and MEK2 during mouse development. Cell Growth Differ 8:505-11
Lee, K S; Erikson, R L (1997) Plk is a functional homolog of Saccharomyces cerevisiae Cdc5, and elevated Plk activity induces multiple septation structures. Mol Cell Biol 17:3408-17

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