Agency
National Institute of Health (NIH)
Institute
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37AA010030-09
Application #
6626415
Study Section
Special Emphasis Panel (NSS)
Program Officer
Sorensen, Roger
Project Start
1995-01-01
Project End
2004-12-31
Budget Start
2003-01-01
Budget End
2003-12-31
Support Year
9
Fiscal Year
2003
Total Cost
$595,384
Indirect Cost
Name
Ernest Gallo Clinic and Research Center
Department
Type
DUNS #
173995366
City
Emeryville
State
CA
Country
United States
Zip Code
94608
Fan, Peidong; Jiang, Zhan; Diamond, Ivan et al. (2009) Up-regulation of AGS3 during morphine withdrawal promotes cAMP superactivation via adenylyl cyclase 5 and 7 in rat nucleus accumbens/striatal neurons. Mol Pharmacol 76:526-33
Bowers, M Scott; Hopf, F Woodward; Chou, Jonathan K et al. (2008) Nucleus accumbens AGS3 expression drives ethanol seeking through G betagamma. Proc Natl Acad Sci U S A 105:12533-8
Yao, Lina; McFarland, Krista; Fan, Peidong et al. (2005) Activator of G protein signaling 3 regulates opiate activation of protein kinase A signaling and relapse of heroin-seeking behavior. Proc Natl Acad Sci U S A 102:8746-51
Arolfo, Maria Pia; Yao, Lina; Gordon, Adrienne S et al. (2004) Ethanol operant self-administration in rats is regulated by adenosine A2 receptors. Alcohol Clin Exp Res 28:1308-16
Souroujon, Miriam C; Yao, Lina; Chen, Haibin et al. (2004) State-specific monoclonal antibodies identify an intermediate state in epsilon protein kinase C activation. J Biol Chem 279:17617-24
Constantinescu, Anastasia; Wu, Meiye; Asher, Orna et al. (2004) cAMP-dependent protein kinase type I regulates ethanol-induced cAMP response element-mediated gene expression via activation of CREB-binding protein and inhibition of MAPK. J Biol Chem 279:43321-9
Mailliard, William S; Diamond, Ivan (2004) Recent advances in the neurobiology of alcoholism: the role of adenosine. Pharmacol Ther 101:39-46
Yao, Lina; Fan, Peidong; Jiang, Zhan et al. (2003) Addicting drugs utilize a synergistic molecular mechanism in common requiring adenosine and Gi-beta gamma dimers. Proc Natl Acad Sci U S A 100:14379-84
Constantinescu, Anastasia; Gordon, Adrienne S; Diamond, Ivan (2002) cAMP-dependent protein kinase types I and II differentially regulate cAMP response element-mediated gene expression: implications for neuronal responses to ethanol. J Biol Chem 277:18810-6
Yao, Lina; Arolfo, Maria Pia; Dohrman, Douglas P et al. (2002) betagamma Dimers mediate synergy of dopamine D2 and adenosine A2 receptor-stimulated PKA signaling and regulate ethanol consumption. Cell 109:733-43

Showing the most recent 10 out of 12 publications