Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
3R37AG006036-18S1
Application #
6760837
Study Section
Special Emphasis Panel (NSS)
Program Officer
Wagster, Molly V
Project Start
1985-12-01
Project End
2008-06-30
Budget Start
2003-07-15
Budget End
2004-06-30
Support Year
18
Fiscal Year
2003
Total Cost
$44,145
Indirect Cost
Name
Yale University
Department
Neurosciences
Type
Schools of Medicine
DUNS #
043207562
City
New Haven
State
CT
Country
United States
Zip Code
06520
Arnsten, Amy F T; Pliszka, Steven R (2011) Catecholamine influences on prefrontal cortical function: relevance to treatment of attention deficit/hyperactivity disorder and related disorders. Pharmacol Biochem Behav 99:211-6
Arnsten, Amy F T (2011) Catecholamine influences on dorsolateral prefrontal cortical networks. Biol Psychiatry 69:e89-99
Arnsten, Amy F T (2011) Prefrontal cortical network connections: key site of vulnerability in stress and schizophrenia. Int J Dev Neurosci 29:215-23
Arnsten, Amy F T; Paspalas, Constantinos D; Gamo, Nao J et al. (2010) Dynamic Network Connectivity: A new form of neuroplasticity. Trends Cogn Sci 14:365-75
Salloway, S; Sperling, R; Gilman, S et al. (2009) A phase 2 multiple ascending dose trial of bapineuzumab in mild to moderate Alzheimer disease. Neurology 73:2061-70
Brennan, Avis R; Yuan, Peixiong; Dickstein, Dara L et al. (2009) Protein kinase C activity is associated with prefrontal cortical decline in aging. Neurobiol Aging 30:782-92
Arnsten, Amy F T (2009) Stress signalling pathways that impair prefrontal cortex structure and function. Nat Rev Neurosci 10:410-22
Arnsten, Amy F T (2009) Toward a new understanding of attention-deficit hyperactivity disorder pathophysiology: an important role for prefrontal cortex dysfunction. CNS Drugs 23 Suppl 1:33-41
Hains, Avis Brennan; Vu, Mai Anh T; Maciejewski, Paul K et al. (2009) Inhibition of protein kinase C signaling protects prefrontal cortex dendritic spines and cognition from the effects of chronic stress. Proc Natl Acad Sci U S A 106:17957-62
Arnsten, Amy F T (2009) The Emerging Neurobiology of Attention Deficit Hyperactivity Disorder: The Key Role of the Prefrontal Association Cortex. J Pediatr 154:I-S43

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