Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
4R37AG006168-25
Application #
8223002
Study Section
Special Emphasis Panel (NSS)
Program Officer
Guo, Max
Project Start
1986-05-01
Project End
2017-03-31
Budget Start
2012-04-01
Budget End
2013-03-31
Support Year
25
Fiscal Year
2012
Total Cost
$322,643
Indirect Cost
$108,262
Name
Tulane University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
053785812
City
New Orleans
State
LA
Country
United States
Zip Code
70118
Malik, Deepika; Hsu, Tiffany; Falatoonzadeh, Payam et al. (2014) Human retinal transmitochondrial cybrids with J or H mtDNA haplogroups respond differently to ultraviolet radiation: implications for retinal diseases. PLoS One 9:e99003
Jazwinski, S Michal (2014) The retrograde response: a conserved compensatory reaction to damage from within and from without. Prog Mol Biol Transl Sci 127:133-54
Kenney, M Cristina; Chwa, Marilyn; Atilano, Shari R et al. (2014) Inherited mitochondrial DNA variants can affect complement, inflammation and apoptosis pathways: insights into mitochondrial-nuclear interactions. Hum Mol Genet 23:3537-51
Kenney, M Cristina; Chwa, Marilyn; Atilano, Shari R et al. (2014) Molecular and bioenergetic differences between cells with African versus European inherited mitochondrial DNA haplogroups: implications for population susceptibility to diseases. Biochim Biophys Acta 1842:208-19
Jazwinski, S Michal (2013) The retrograde response: when mitochondrial quality control is not enough. Biochim Biophys Acta 1833:400-9
Kenney, M Cristina; Chwa, Marilyn; Atilano, Shari R et al. (2013) Mitochondrial DNA variants mediate energy production and expression levels for CFH, C3 and EFEMP1 genes: implications for age-related macular degeneration. PLoS One 8:e54339
Srinivasan, Visish; Kriete, Andres; Sacan, Ahmet et al. (2010) Comparing the yeast retrograde response and NF-?B stress responses: implications for aging. Aging Cell 9:933-41
Wang, Jinqing; Jiang, James C; Jazwinski, S Michal (2010) Gene regulatory changes in yeast during life extension by nutrient limitation. Exp Gerontol 45:621-31
Ponnusamy, Suriyan; Alderson, Nathan L; Hama, Hiroko et al. (2008) Regulation of telomere length by fatty acid elongase 3 in yeast. Involvement of inositol phosphate metabolism and Ku70/80 function. J Biol Chem 283:27514-24
Senkal, Can E; Ponnusamy, Suriyan; Rossi, Michael J et al. (2007) Role of human longevity assurance gene 1 and C18-ceramide in chemotherapy-induced cell death in human head and neck squamous cell carcinomas. Mol Cancer Ther 6:712-22

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