Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
4R37AG006168-25
Application #
8223002
Study Section
Special Emphasis Panel (NSS)
Program Officer
Guo, Max
Project Start
1986-05-01
Project End
2017-03-31
Budget Start
2012-04-01
Budget End
2013-03-31
Support Year
25
Fiscal Year
2012
Total Cost
$322,643
Indirect Cost
$108,262
Name
Tulane University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
053785812
City
New Orleans
State
LA
Country
United States
Zip Code
70118
Jazwinski, S Michal; Jiang, James C; Kim, Sangkyu (2018) Adaptation to metabolic dysfunction during aging: Making the best of a bad situation. Exp Gerontol 107:87-90
Kerur, Nagaraj; Fukuda, Shinichi; Banerjee, Daipayan et al. (2018) cGAS drives noncanonical-inflammasome activation in age-related macular degeneration. Nat Med 24:50-61
Thaker, Kunal; Chwa, Marilyn; Atilano, Shari R et al. (2016) Increased expression of ApoE and protection from amyloid-beta toxicity in transmitochondrial cybrids with haplogroup K mtDNA. Neurobiol Dis 93:64-77
Zaman, Shamsu; Choudhury, Malay; Jiang, James C et al. (2016) Mechanism of Regulation of Intrachromatid Recombination and Long-Range Chromosome Interactions in Saccharomyces cerevisiae. Mol Cell Biol 36:1451-63
Jiang, James C; Stumpferl, Stefan W; Tiwari, Anurag et al. (2016) Identification of the Target of the Retrograde Response that Mediates Replicative Lifespan Extension in Saccharomyces cerevisiae. Genetics 204:659-673
Svenkrtova, Andrea; Belicova, Lenka; Volejnikova, Andrea et al. (2016) Stratification of yeast cells during chronological aging by size points to the role of trehalose in cell vitality. Biogerontology 17:395-408
Choudhury, Malay; Zaman, Shamsu; Jiang, James C et al. (2015) Mechanism of regulation of 'chromosome kissing' induced by Fob1 and its physiological significance. Genes Dev 29:1188-201
Jazwinski, S M (2015) Mitochondria to nucleus signaling and the role of ceramide in its integration into the suite of cell quality control processes during aging. Ageing Res Rev 23:67-74
Atilano, Shari R; Malik, Deepika; Chwa, Marilyn et al. (2015) Mitochondrial DNA variants can mediate methylation status of inflammation, angiogenesis and signaling genes. Hum Mol Genet 24:4491-503
Kenney, M Cristina; Chwa, Marilyn; Atilano, Shari R et al. (2014) Inherited mitochondrial DNA variants can affect complement, inflammation and apoptosis pathways: insights into mitochondrial-nuclear interactions. Hum Mol Genet 23:3537-51

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