Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37AG024360-12
Application #
9251727
Study Section
Special Emphasis Panel (NSS)
Program Officer
Guo, Max
Project Start
2016-04-01
Project End
2021-03-31
Budget Start
2017-04-01
Budget End
2018-03-31
Support Year
12
Fiscal Year
2017
Total Cost
$402,022
Indirect Cost
$149,853
Name
Brown University
Department
Biology
Type
Schools of Medicine
DUNS #
001785542
City
Providence
State
RI
Country
United States
Zip Code
02912
Post, Stephanie; Karashchuk, Galina; Wade, John D et al. (2018) Drosophila Insulin-Like Peptides DILP2 and DILP5 Differentially Stimulate Cell Signaling and Glycogen Phosphorylase to Regulate Longevity. Front Endocrinol (Lausanne) 9:245
Zheng, Wenjing; Rus, Florentina; Hernandez, Ana et al. (2018) Dehydration triggers ecdysone-mediated recognition-protein priming and elevated anti-bacterial immune responses in Drosophila Malpighian tubule renal cells. BMC Biol 16:60
Lin, Feng; Hossain, Mohammed Akhter; Post, Stephanie et al. (2017) Total Solid-Phase Synthesis of Biologically Active Drosophila Insulin-Like Peptide 2 (DILP2). Aust J Chem 70:208-212
Kang, Ping; Chang, Kai; Liu, Ying et al. (2017) Drosophila Kruppel homolog 1 represses lipolysis through interaction with dFOXO. Sci Rep 7:16369
Post, Stephanie; Tatar, Marc (2016) Nutritional Geometric Profiles of Insulin/IGF Expression in Drosophila melanogaster. PLoS One 11:e0155628
Bowman, Elizabeth; Tatar, Marc (2016) Reproduction regulates Drosophila nutrient intake through independent effects of egg production and sex peptide: Implications for aging. Nutr Healthy Aging 4:55-61
Tatar, Marc; Sedivy, John M (2016) Mitochondria: Masters of Epigenetics. Cell 165:1052-1054
Bai, Hua; Post, Stephanie; Kang, Ping et al. (2015) Drosophila Longevity Assurance Conferred by Reduced Insulin Receptor Substrate Chico Partially Requires d4eBP. PLoS One 10:e0134415
Tatar, Marc; Post, Stephanie; Yu, Kweon (2014) Nutrient control of Drosophila longevity. Trends Endocrinol Metab 25:509-17
Ding, Feifei; Gil, M Pilar; Franklin, Michael et al. (2014) Transcriptional response to dietary restriction in Drosophila melanogaster. J Insect Physiol 69:101-6

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