Comparative effectiveness research (CER) is intended to measure how alternative approaches to health care affect health outcomes. CER has the potential to reduce expenditures by limiting the use of both ineffective care and care that is no more effective than less costly alternatives. We propose to study the benefits that might accrue to Medicare from the application of CER to six high- priority medical areas.
Our specific aims are to: 1. Identify areas of CER that have the greatest potential to improve the efficiency and appropriateness of care delivered to Medicare beneficiaries. 2. Estimate (long-term) incremental expenditures attributable to the use of competing strategies in these high-priority clinical areas. 3. Determine the expenditure implications for Medicare that would result from the adoption of clinical strategies supported by CER criteria, including cost-effectiveness, for each high-priority area, and to describe policy options (e.g. reference pricing, bundled payments, etc.) for implementing these findings for Medicare. Our analyses are principally based on complete Medicare claims files for Parts A and B from years 1991 to 2009 and Part D from 2006 to 2009. Data for the analysis of cancer management (e.g., localized prostate cancer), will include SEER-Medicare linked data. We will first select the medical areas for further research based upon a prioritization process considering, for each potential area of investigation, effects on total Medicare expenditures, potential for growth, and evidence of variability or uncertainty in clinical approaches. A distinguished expert Advisory Committee, representing health care, health insurance, and consumer perspectives, will provide close guidance for this component and several other aspects of the project. For each high-priority medical area selected, we will identify the relevant cohort from the Medicare claims files (or SEER-Medicare files) and assign individuals to management strategies based upon treatment or diagnostic interventions received. In addition to descriptive statistical analyses (frequency of the use of each strategy, rates of important outcomes, and total and related health expenditures), the project will include multivariate statistical analysis to investigate the relationship between strategy, outcome (including expenditures) and key variables. Where possible, we will use instrumental variable analysis and related techniques to control for bias in the selection of management strategies. Separate models will be estimated for important subgroups. We will estimate the potential consequences to Medicare of implementing our findings for each medical area by constructing a population model that shifts (with scenarios of varying degrees of adoption) patients to the strategy(ies) supported by our findings (least costly with equivalent outcomes or additional cost worth the incremental benefit based on cost-effectiveness analysis). Finally, we will investigate approaches that Medicare might use to implement these findings, including payment reform options such as bundled payments, reference pricing and value-based copayments.
This project identifies clinical strategies supported by comparative-effectiveness research that have the potential, through greater use, to decrease costs to Medicare without adversely affecting health outcomes. It estimates the long-term impact on expenditures of shifting current clinical practices to these strategies and evaluates options for implementing these findings.
|Erickson, Kevin F; Mell, Matthew; Winkelmayer, Wolfgang C et al. (2015) Provider Visits and Early Vascular Access Placement in Maintenance Hemodialysis. J Am Soc Nephrol 26:1990-7|
|Gidwani, Risha; Bhattacharya, Jay (2015) CMS Reimbursement Reform. J Gen Intern Med 30:1588|
|Chicklis, Camille; MaCurdy, Thomas; Bhattacharya, Jay et al. (2015) Regional Growth in Medicare Spending, 1992-2010. Health Serv Res 50:1574-88|
|Erickson, Kevin F; Mell, Matthew W; Winkelmayer, Wolfgang C et al. (2015) Provider visit frequency and vascular access interventions in hemodialysis. Clin J Am Soc Nephrol 10:269-77|
|Romley, John A; Axeen, Sarah; Lakdawalla, Darius N et al. (2015) The Relationship between Commercial Health Care Prices and Medicare Spending and Utilization. Health Serv Res 50:883-96|
|Jena, Anupam B; Schoemaker, Lena; Bhattacharya, Jay et al. (2015) Physician spending and subsequent risk of malpractice claims: observational study. BMJ 351:h5516|
|Erickson, Kevin F; Winkelmayer, Wolfgang C; Chertow, Glenn M et al. (2014) Medicare Reimbursement Reform for Provider Visits and Health Outcomes in Patients on Hemodialysis. Forum Health Econ Policy 17:53-77|
|Simons, Cyrena T; Cipriano, Lauren E; Shah, Rashmee U et al. (2013) Transcatheter aortic valve replacement in nonsurgical candidates with severe, symptomatic aortic stenosis: a cost-effectiveness analysis. Circ Cardiovasc Qual Outcomes 6:419-28|
|Perlroth, Daniella J; Bhattacharya, Jay; Goldman, Dana P et al. (2012) An economic analysis of conservative management versus active treatment for men with localized prostate cancer. J Natl Cancer Inst Monogr 2012:250-7|
|Bryan, Christopher J; Hershfield, Hal E (2012) You owe it to yourself: boosting retirement saving with a responsibility-based appeal. J Exp Psychol Gen 141:429-32|