Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
4R37DK033209-31
Application #
8600342
Study Section
Special Emphasis Panel (NSS)
Program Officer
Grey, Michael J
Project Start
1983-12-01
Project End
2018-02-28
Budget Start
2013-03-15
Budget End
2014-02-28
Support Year
31
Fiscal Year
2013
Total Cost
$340,875
Indirect Cost
$115,875
Name
University of Arizona
Department
Pediatrics
Type
Schools of Medicine
DUNS #
806345617
City
Tucson
State
AZ
Country
United States
Zip Code
85721
Larmonier, Claire B; Shehab, Kareem W; Laubitz, Daniel et al. (2016) Transcriptional Reprogramming and Resistance to Colonic Mucosal Injury in Poly(ADP-ribose) Polymerase 1 (PARP1)-deficient Mice. J Biol Chem 291:8918-30
Radhakrishnan, Vijayababu M; Kojs, Pawel; Ramalingam, Rajalakshmy et al. (2015) Experimental colitis is associated with transcriptional inhibition of Na+/Ca2+ exchanger isoform 1 (NCX1) expression by interferon γ in the renal distal convoluted tubules. J Biol Chem 290:8964-74
Ghishan, Fayez K; Kiela, Pawel R (2014) Epithelial transport in inflammatory bowel diseases. Inflamm Bowel Dis 20:1099-109
Radhakrishnan, Vijayababu M; Ramalingam, Rajalakshmy; Larmonier, Claire B et al. (2013) Post-translational loss of renal TRPV5 calcium channel expression, Ca(2+) wasting, and bone loss in experimental colitis. Gastroenterology 145:613-24
Larmonier, C B; McFadden, R-M T; Hill, F M et al. (2013) High vitamin D3 diet administered during active colitis negatively affects bone metabolism in an adoptive T cell transfer model. Am J Physiol Gastrointest Liver Physiol 305:G35-46
Ghishan, Fayez K; Kiela, Pawel R (2012) Small intestinal ion transport. Curr Opin Gastroenterol 28:130-4
Ghishan, Fayez K; Kiela, Pawel R (2011) Advances in the understanding of mineral and bone metabolism in inflammatory bowel diseases. Am J Physiol Gastrointest Liver Physiol 300:G191-201
Kiela, Pawel R (2010) Unraveling the pathophysiology of alcohol-induced thiamin deficiency. Am J Physiol Renal Physiol 299:F26-7
Majewski, Pawel M; Thurston, Robert D; Ramalingam, Rajalakshmy et al. (2010) Cooperative role of NF-{kappa}B and poly(ADP-ribose) polymerase 1 (PARP-1) in the TNF-induced inhibition of PHEX expression in osteoblasts. J Biol Chem 285:34828-38
Thurston, Robert D; Larmonier, Claire B; Majewski, Pawel M et al. (2010) Tumor necrosis factor and interferon-gamma down-regulate Klotho in mice with colitis. Gastroenterology 138:1384-94, 1394.e1-2

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