Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37GM024266-20
Application #
2174232
Study Section
Molecular and Cellular Biophysics Study Section (BBCA)
Project Start
1977-08-01
Project End
1998-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
20
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Pennsylvania
Department
Chemistry
Type
Schools of Arts and Sciences
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19104
Sinha, Neeraj; Grant, Christopher V; Wu, Chin H et al. (2005) SPINAL modulated decoupling in high field double- and triple-resonance solid-state NMR experiments on stationary samples. J Magn Reson 177:197-202
Nevzorov, Alexander A; Mesleh, Michael F; Opella, Stanley J (2004) Structure determination of aligned samples of membrane proteins by NMR spectroscopy. Magn Reson Chem 42:162-71
Opella, Stanley J (2003) Membrane protein NMR studies. Methods Mol Biol 227:307-20
Nevzorov, Alexander A; Opella, Stanley J (2003) Structural fitting of PISEMA spectra of aligned proteins. J Magn Reson 160:33-9
Mesleh, M F; Valentine, K G; Opella, S J et al. (2003) Myristoylation as a general method for immobilization and alignment of soluble proteins for solid-state NMR structural studies. J Biomol NMR 25:55-61
Nevzorov, Alexander A; Opella, Stanley J (2003) A ""magic sandwich"" pulse sequence with reduced offset dependence for high-resolution separated local field spectroscopy. J Magn Reson 164:182-6
Mesleh, Michael F; Lee, Sangwon; Veglia, Gianluigi et al. (2003) Dipolar waves map the structure and topology of helices in membrane proteins. J Am Chem Soc 125:8928-35
Park, Sang Ho; Mrse, Anthony A; Nevzorov, Alexander A et al. (2003) Three-dimensional structure of the channel-forming trans-membrane domain of virus protein ""u"" (Vpu) from HIV-1. J Mol Biol 333:409-24
Zeri, Ana Carolina; Mesleh, Michael F; Nevzorov, Alexander A et al. (2003) Structure of the coat protein in fd filamentous bacteriophage particles determined by solid-state NMR spectroscopy. Proc Natl Acad Sci U S A 100:6458-63
Lee, Sangwon; Mesleh, Michael F; Opella, Stanley J (2003) Structure and dynamics of a membrane protein in micelles from three solution NMR experiments. J Biomol NMR 26:327-34

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