Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37GM036373-28
Application #
8242040
Study Section
Special Emphasis Panel (NSS)
Program Officer
Ainsztein, Alexandra M
Project Start
1993-06-01
Project End
2013-03-31
Budget Start
2012-04-01
Budget End
2013-03-31
Support Year
28
Fiscal Year
2012
Total Cost
$415,318
Indirect Cost
$170,293
Name
Harvard University
Department
Biology
Type
Schools of Medicine
DUNS #
047006379
City
Boston
State
MA
Country
United States
Zip Code
02115
Wang, Qingqing; Moore, Michael J; Adelmant, Guillaume et al. (2013) PQBP1, a factor linked to intellectual disability, affects alternative splicing associated with neurite outgrowth. Genes Dev 27:615-26
Lohmueller, Jason J; Armel, Thomas Z; Silver, Pamela A (2012) A tunable zinc finger-based framework for Boolean logic computation in mammalian cells. Nucleic Acids Res 40:5180-7
Boyle, Patrick M; Silver, Pamela A (2012) Parts plus pipes: synthetic biology approaches to metabolic engineering. Metab Eng 14:223-32
Smolke, Christina D; Silver, Pamela A (2011) Informing biological design by integration of systems and synthetic biology. Cell 144:855-9
Shih, Joseph D; Waks, Zeev; Kedersha, Nancy et al. (2011) Visualization of single mRNAs reveals temporal association of proteins with microRNA-regulated mRNA. Nucleic Acids Res 39:7740-9
Senapedis, William T; Kennedy, Caleb J; Boyle, Patrick M et al. (2011) Whole genome siRNA cell-based screen links mitochondria to Akt signaling network through uncoupling of electron transport chain. Mol Biol Cell 22:1791-805
Burrill, Devin R; Silver, Pamela A (2011) Synthetic circuit identifies subpopulations with sustained memory of DNA damage. Genes Dev 25:434-9
Burrill, Devin R; Silver, Pamela A (2011) Recording cellular experiences of DNA damage. Cell Cycle 10:2410-1
Waks, Zeev; Klein, Allon M; Silver, Pamela A (2011) Cell-to-cell variability of alternative RNA splicing. Mol Syst Biol 7:506
Haynes, Karmella A; Silver, Pamela A (2011) Synthetic reversal of epigenetic silencing. J Biol Chem 286:27176-82

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