Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37HD021502-19
Application #
6846041
Study Section
Special Emphasis Panel (NSS)
Program Officer
Klein, Steven
Project Start
1986-04-01
Project End
2007-01-31
Budget Start
2005-02-01
Budget End
2006-01-31
Support Year
19
Fiscal Year
2005
Total Cost
$355,022
Indirect Cost
Name
University of California Los Angeles
Department
Biochemistry
Type
Schools of Medicine
DUNS #
092530369
City
Los Angeles
State
CA
Country
United States
Zip Code
90095
Ploper, Diego; Taelman, Vincent F; Robert, Lidia et al. (2015) MITF drives endolysosomal biogenesis and potentiates Wnt signaling in melanoma cells. Proc Natl Acad Sci U S A 112:E420-9
Colozza, Gabriele; De Robertis, Edward M (2014) Maternal syntabulin is required for dorsal axis formation and is a germ plasm component in Xenopus. Differentiation 88:17-26
Plouhinec, Jean-Louis; Zakin, Lise; Moriyama, Yuki et al. (2013) Chordin forms a self-organizing morphogen gradient in the extracellular space between ectoderm and mesoderm in the Xenopus embryo. Proc Natl Acad Sci U S A 110:20372-9
Dobrowolski, Radek; Vick, Philipp; Ploper, Diego et al. (2012) Presenilin deficiency or lysosomal inhibition enhances Wnt signaling through relocalization of GSK3 to the late-endosomal compartment. Cell Rep 2:1316-28
Ploper, Diego; Lee, Hojoon X; De Robertis, Edward M (2011) Dorsal-ventral patterning: Crescent is a dorsally secreted Frizzled-related protein that competitively inhibits Tolloid proteases. Dev Biol 352:317-28
Vorwald-Denholtz, Peggy P; De Robertis, Edward M (2011) Temporal pattern of the posterior expression of Wingless in Drosophila blastoderm. Gene Expr Patterns 11:456-63
Eivers, Edward; Demagny, Hadrien; Choi, Renee H et al. (2011) Phosphorylation of Mad controls competition between wingless and BMP signaling. Sci Signal 4:ra68
Plouhinec, Jean-Louis; Zakin, Lise; De Robertis, Edward M (2011) Systems control of BMP morphogen flow in vertebrate embryos. Curr Opin Genet Dev 21:696-703
Taelman, Vincent F; Dobrowolski, Radoslaw; Plouhinec, Jean-Louis et al. (2010) Wnt signaling requires sequestration of glycogen synthase kinase 3 inside multivesicular endosomes. Cell 143:1136-48
Sander, Veronika; Eivers, Edward; Choi, Renee H et al. (2010) Drosophila Smad2 opposes Mad signaling during wing vein development. PLoS One 5:e10383

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