AudioFile proposes to create a software """"""""tool"""""""" to characterize aspects of the structure and performance of the larynx from analysis of speech. The analysis relies on the theory of nonlinear dynamical systems, or """"""""chaos theory"""""""". It provides parameters (Lyapunov exponents, metric entropy, attractor dimensions) which cannot be derived from conventional reduction but which have already been shown to have value in characterizing the larynx as a dynamical system. The technique is non- invasive, and the software will accept continuous speech and even some unrequested vocalizations, as from neonates. The tool will be capable of detecting both unusual glottal periodicities and complete aperiodicity (chaos). There are both physiological and mathematical reasons to expect some distinct pathologies to excite distinct dynamical responses which the tool can distinguish. Phase I will: verify that the tool can reliably determine the exponents and the attractor dimensions for entries in an existing digital data base of vocalizations; show that the parameters identify distinct modes of stable vibration; and determine the extent to which the parameters vary with known laryngeal conditions. If successful, this software will provide a new set of clinical """"""""measurements"""""""" for assisting in the diagnosis of laryngeal pathologies. It can then provide objective corroboration for clinical judgments.

Agency
National Institute of Health (NIH)
Institute
National Institute on Deafness and Other Communication Disorders (NIDCD)
Type
Small Business Innovation Research Grants (SBIR) - Phase II (R44)
Project #
5R44DC002343-03
Application #
2391122
Study Section
Special Emphasis Panel (ZRG1-CMS (02))
Project Start
1996-04-01
Project End
1999-03-31
Budget Start
1997-04-01
Budget End
1999-03-31
Support Year
3
Fiscal Year
1997
Total Cost
Indirect Cost
Name
Speech Technology/Applied Research Corp.
Department
Type
DUNS #
City
Bedford
State
MA
Country
United States
Zip Code
01730