Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
High Priority, Short Term Project Award (R56)
Project #
1R56AI067544-01A1
Application #
7270206
Study Section
Cellular and Molecular Immunology - B Study Section (CMIB)
Program Officer
Sawyer, Richard T
Project Start
2006-08-15
Project End
2007-04-14
Budget Start
2006-08-15
Budget End
2007-04-14
Support Year
1
Fiscal Year
2006
Total Cost
$253,449
Indirect Cost
Name
University of Pittsburgh
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
004514360
City
Pittsburgh
State
PA
Country
United States
Zip Code
15213
Phong, Binh; Avery, Lyndsay; Menk, Ashley V et al. (2017) Cutting Edge: Murine Mast Cells Rapidly Modulate Metabolic Pathways Essential for Distinct Effector Functions. J Immunol 198:640-644
Phong, Binh L; Avery, Lyndsay; Sumpter, Tina L et al. (2015) Tim-3 enhances Fc?RI-proximal signaling to modulate mast cell activation. J Exp Med 212:2289-304
Ferris, Robert L; Lu, Binfeng; Kane, Lawrence P (2014) Too much of a good thing? Tim-3 and TCR signaling in T cell exhaustion. J Immunol 193:1525-30
Su, Ee W; Bi, Shuguang; Kane, Lawrence P (2011) Galectin-9 regulates T helper cell function independently of Tim-3. Glycobiology 21:1258-65
Lee, Judong; Su, Ee Wern; Zhu, Chen et al. (2011) Phosphotyrosine-dependent coupling of Tim-3 to T-cell receptor signaling pathways. Mol Cell Biol 31:3963-74
Lee, J; Phong, B; Egloff, A M et al. (2011) TIM polymorphisms--genetics and function. Genes Immun 12:595-604
Kane, Lawrence P (2010) T cell Ig and mucin domain proteins and immunity. J Immunol 184:2743-9
Ho, Allen W; Shen, Fang; Conti, Heather R et al. (2010) IL-17RC is required for immune signaling via an extended SEF/IL-17R signaling domain in the cytoplasmic tail. J Immunol 185:1063-70