Funding is requested for a cryogenically cooled probe, preamplifier and helium recovery system for our shared 600 MHz NMR spectrometer. The addition of this cooled probe will greatly facilitate the research of the several research groups that are using or plan to use modern NMR techniques in their work. These groups are working on a wide range of projects that include investigations of the structure, function and dynamics of the proteins involved in bacterial signaling during bacterial chemotaxis and related signaling pathways; protein folding dynamics and the nature of the unfolded state; the structure of self assembly of RNA-RNA recognition units, the coupling of protein dynamics and catalysis in the bacterial DNA cytosine methyltransferase, structural studies of the proteins involved in the epigenetic control of the expression of genes that encode proteins present in pyelonephritis-associated pili; the structure an assembly of tau protein; structural elucidation of marine siderophores; proteins and models of biomineralization; and kinetic analysis of the acetylcholine transporter. ? ?
| Yan, Hengjing; Chuang, Chern; Zhugayevych, Andriy et al. (2015) Inter-aromatic distances in Geobacter sulfurreducens pili relevant to biofilm charge transport. Adv Mater 27:1908-11 |
| Kirchhofer, Nathan D; Chen, Xiaofen; Marsili, Enrico et al. (2014) The conjugated oligoelectrolyte DSSN+ enables exceptional coulombic efficiency via direct electron transfer for anode-respiring Shewanella oneidensis MR-1-a mechanistic study. Phys Chem Chem Phys 16:20436-43 |
| Levenson, Robert; Zhou, Hongjun; Dahlquist, Frederick W (2012) Structural insights into the interaction between the bacterial flagellar motor proteins FliF and FliG. Biochemistry 51:5052-60 |
| Kawamura, Tetsuya; Le, Lisa Uyen K; Zhou, Hongjun et al. (2007) Solution structure of Escherichia coli PapI, a key regulator of the pap pili phase variation. J Mol Biol 365:1130-42 |
